ISSN:
1573-1111
Keywords:
Selectivity
;
hemoglobin
;
myoglobin
;
O2 transport
;
O2 binding
;
O2 carrier
;
cytochrome P450
;
synthetic enzymes
;
biomimics
;
molecular cavity
;
cyclidene
;
superstructure
;
lacuna
;
molecular design
;
host/guest complex
;
quarternary complex
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Early attention to the modeling of heme proteins is enhancing the understanding of biochemistry. Those studies are also contributing to the development of techniques for the modeling of still more intricate, multifunctional, variously selective natural systems. Selectivity in simple systems may involve the molecular capability to bind only one of a family of related species or it may mean the ability to select and control one of a number of possible functions of a given bound species. Complicated systems simultaneously combine the two kinds of simple selectivities for two or more different classes of guest, often with synergistic interrelationships. The subject is developed around examples of binary, tertiary, and quarternary complexes designed to model the behavior of monooxygenases.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01060716
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