ISSN:
1476-5535
Keywords:
Metabolite overproduction
;
ATP/O quotient
;
ATP turnover
;
Energetics
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Summary Data regarding the degree of energy conservation as determined by the $$Y_{O_2 }^{\max } $$ and the highest rates of metabolite production reported for various micro-organisms have been collated and analysed. The results have indicated that the highest rates of metabolite production occur in micro-organisms possessing low efficiencies of energy conservation. Moreover, in the case of exopolysaccharide production the oxidation state of the polymer is inversely related to the $$Y_{O_2 }^{\max } $$ value of the producing organism. In general, the rate of ATP turnover associated with exopolysaccharide production or the potential rate associated with over-production of other metabolites is inversely related to the $$Y_{O_2 }^{\max } $$ value of the producing organism. Analysis of current production rates for a range of metabolites suggests that there is scope for major improvements of existing processes by careful selection of appropriate micro-organisms.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01569792
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