ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Rapid Communications in Mass Spectrometry 7 (1993), S. 1145-1149 
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: A method that combines gas chromatography and mass spectrometry (GC/MS) for the determination of N-0923 in human and monkey plasma is detailed. This novel drug holds promise for the treatment of Parkinson's disease. Clinical use of N-0923 will result both in low peak plasma concentrations and in a short half-life; consequently, a highly sensitive method will be required. Previous methods using high-performance liquid chromatography with electrochemical detection have given reliable data in high dose studies in animals to 0.3-1.0 ng/mL in plasma but are not considered adequate for studies at clinical levels in humans. The data in this paper will show that GC/MS can offer a new direction in the determination of N-0923 in human and monkey samples, with reliable data to 25 pg/mL in plasma. This method is presented as a novel approach to the determination of N-0923, and as a starting point for further development.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A sensitive and specific assay for the quantitative determination of amphetamine, methamphetamine and desmethyldeprenyl in human plasma specimens is described. Electron capture/negative ion chemical ionization gas chromatography/mass spectrometry is used to determine the extracted plasma concentrations of the three target compounds as their N-heptafluorobutyryl derivatives. Quantitation is performed by stable isotope dilution using d6-amphetamine and d6-methamphetamine as internal standards. Selected ion monitoring of the [M - HF]- ions of both the analytes and internal standards results in minimum quantifiable limits of 0.10 ng ml-1 for both amphetamine and methamphetamine and 0.25 ng ml-1 for desmethyldeprenyl. Excellent linearity (r = 0.998) up to at least 5.00 ng ml-1 is demonstrated.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    Publication Date: 2016-11-24
    Keywords: coral ; reef ; Malaysia
    Repository Name: National Museum of Natural History, Netherlands
    Type: Book (monograph)
    Format: application/pdf
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    Publication Date: 2024-01-12
    Description: Much remains to be discovered about the biodiversity of coral reefs in Malaysia, making this area a priority for coral reef research. This thesis aims to provide insights into the patterns of reef coral species richness and the degree of reef connectivity across Malaysia. For the species richness study, the scleractinian coral families Fungiidae, Agariciidae and Euphylliidae were selected as model taxa. Species of these families have a wide geographical distribution in the Indo-Pacific, and they can be found in a large range of reef habitats, from shallow coastal reefs to deep offshore environments. The connectivity of reefs were inferred by examining the genetic population structures of three reef invertebrate species, the mushroom coral Heliofungia actiniformis, the blue seastar Linckia laevigata, and the boring giant clam Tridacna crocea. Data on coral species and specimens of reef invertebrates were collected from reef areas along a geographical range from east to west Malaysia. Reef coral species richness patterns were revealed and indicated common and rare species, as well as potential endemics. Factors to explain the population structure and connectivity patterns across Malaysia are discussed. The findings in this thesis may be relevant for conservation and management of coral reef areas in Malaysia.
    Keywords: coral ; reef ; Malaysia ; Biodiversity ; Coral Triangle ; Population genetics ; Reef invertebrates ; Species distribution ; Scleractinia
    Repository Name: National Museum of Natural History, Netherlands
    Type: info:eu-repo/semantics/doctoralThesis
    Format: application/pdf
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...