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  • Instrumentation and Photography  (17)
  • Life and Medical Sciences  (7)
  • 1
    Publication Date: 2019-07-12
    Description: At 2015 SPIE O&P we presented "Preliminary Analysis of Random Segment Errors on Coronagraph Performance" Key Findings: Contrast Leakage for 4thorder Sinc2(X) coronagraph is 10X more sensitive to random segment piston than random tip/tilt, Fewer segments (i.e. 1 ring) or very many segments (〉 16 rings) has less contrast leakage as a function of piston or tip/tilt than an aperture with 2 to 4 rings of segments. Revised Findings: Piston is only 2.5X more sensitive than Tip/Tilt
    Keywords: Instrumentation and Photography
    Type: MSFC-E-DAA-TN32194
    Format: application/pdf
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    BioEssays 2 (1985), S. 244-249 
    ISSN: 0265-9247
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Chi sites are examples of special sites enhancing homologous recombination in their region of the chromosome. Chi, 5′ G-C-T-G-G-T-G-G3′, is a recognition site for the RecBC enzyme, which nicks DNA near Chi as it unwinds DNA. A molecular model of genetic recombination incorporating these features is reviewed.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 14 (1993), S. 103-111 
    ISSN: 0192-253X
    Keywords: Mouse ; development ; small heat shock protein ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: We have investigated the developmental and tissue-specific distribution of the mouse small hsp25 by immunohistology using an antibody that specifically identifies hsp25. Our analysis shows that the relative amount of hsp25 increases during embryogenesis. Through days 13-20 of embryogenesis, hsp25 accumulation is predominant in the various muscle tissues, including the heart, the bladder, and the back muscles. hsp25 is detectable also in neurons of the spinal cord and the purkinje cells. Furthermore analysis of the closely related α, B-crystallin shows that in several tissues, including the bladder, the notochordal sheath and the eye lens both proteins are coexpressed. Our studies demonstrate that mammalian hsp25 accumulation is developmentally regulated during mouse embryogenesis and support the view of an important functional role of small heat shock proteins in normal cell metabolism. © 1993Wiley-Liss, Inc.
    Additional Material: 6 Ill.
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  • 4
    ISSN: 0095-9898
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Biologie in unserer Zeit 6 (1976), S. 53-57 
    ISSN: 0045-205X
    Keywords: Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 222 (1994), S. 73-89 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The chimaeroid holocephalian fishes are distinguished among extant chondrichthyans by the possession of three pairs of tooth plates, evergrowing and partially hypermineralized, that are not shed and replaced like the teeth of living elasmobranchs. Although derivation of the chimaeroid tooth plate from the fusion of members of a plesiomorphic chondrichthyan tooth family has been proposed, evidence for this hypothesis has been lacking. A new analysis of the development and structure of the tooth plates in Callorhinchus milii (Holocephali, Chimaeriformes) reveals the compound nature of the tooth plates in a chimaeroid fish. Each tooth plate consists of an oral and aboral territory that form independently in the embryo and maintain separate growth surfaces through life. The descending lamina on the aboral surface of the tooth plate demarcates the growth surface of the aboral territory. Comparison with the tooth plates of Chimaera monstrosa indicates that compound tooth plates may be a feature of all chimaeroids in which a descending lamina is present. The tooth plates in these fishes represent the fusion of two members of a reduced tooth family. The condition of the tooth plates in C. milii is plesiomorphic for chimaeroids and is of evolutionary significance in that it provides further evidence to support a lyodont dentition in chimaeroid fishes similar to that found in other chondrichthyans. © 1994 Wiley-Liss, Inc.
    Additional Material: 14 Ill.
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 70 (1967), S. 1-12 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The widespread occurrence of genetic circularity suggests a selective advantage to map circularity per se. Circularity permits gene clustering relations not possible in linear maps; that is, every gene in a circular map can have two nearest map neighbors, two next nearest, etc. It seems possible that map circularity is a consequence of the selective forces responsible for the clustering of genes of related function. Certain features of the pattern of crossing-over in various fungi suggest that circularity of linkage maps is there to be found. A concurrence of high frequencies of second-division segregation and negative chromatid interference across the centromere, both of which phenomena have been reported, is a feature of a simple hypothetical crossover pattern that generates circular linkage maps.
    Additional Material: 2 Ill.
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Yeast 7 (1991), S. 157-165 
    ISSN: 0749-503X
    Keywords: Translation initiation ; codon usage: mRNA structure ; yeast ; lacZ fusion protein ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: A set of 32 different codons were introduced in a lacZ experssion vector (pPTK400) immediately 3′ from the AUG initiation codon. Expression of the lacZ gene was determined in Saccharomyces cerevisiae by measuring the amount of β-galactosidase fusion protein using immuno-gel electrophoresis. A 5·3-fold difference in expression was found among the various constructs. It was found that there was no preference for a certain nucleotide in any position of the second codon and there was no distinct correlation between the level of tRNA corresponding to any particular second codon and expression. No correlation could be found between the local secondary structure and expression. When the overall codon usage in yeast and the codon usage in the second position of the mRNA is compared, there is no obvious significant difference in preference. This indicates that in yeast, in contrast to Escherichia coli, the codon choice at the beginning of the mRNA does not deviate from the one further downstream and is determined by the requirements for optimal translation elongation. Important determinatnts of the optimal context for an initiation codon in yeast therfore must be located mainly 5′ from this codon.
    Additional Material: 1 Ill.
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  • 9
    Publication Date: 2018-06-12
    Description: Scheduled to begin its 10 year mission no sooner than 2013, the James Webb Space Telescope (JWST) will search for the first luminous objects of the Universe to help answer fundamental questions about how the Universe came to look like it does today. At 6.5 meters in diameter, JWST will be the world's largest space telescope. This talk reviews science objectives for JWST and how they drive the JWST architecture, e.g. aperture, wavelength range and operating temperature. Additionally, the talk provides an overview of the JWST primary mirror technology development and fabrication status.
    Keywords: Instrumentation and Photography
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  • 10
    Publication Date: 2019-07-13
    Description: Technology advancement is required to enable NASA's high priority missions of the future. To prepare for those missions requires a roadmap of how to get from the current state of the art to where technology needs to be in 5, 10, 15 and 20 years. SIOSS identifies where substantial enhancements in mission capabilities are needed and provides strategic guidance for the agency's budget formulation and prioritization process.
    Keywords: Instrumentation and Photography
    Type: M11-1090 , NASA Cosmic Origins Program Analysis Group (COPAG) Meeting; Sep 22, 2011 - Sep 23, 2011; Baltimore, MD; United States
    Format: application/pdf
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