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  • 1
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    Geomagnetic Response to Large-amplitude Interplanetary Alfven Wave Trains (1995)
    In:  Other Sources
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    Publication Date: 2018-06-08
    Description: A review of the geomagnetic response to large-amplitude interplanetary Alfven wave trains is presented, highlighting its dependence on solar activity level and its role in the storm/substorm relationship problem. Also discussed are some recent observations obtained by the Ulysses spacecraft at high heliospheric latitudes dealing with the origin and dynamics of these wave trains.
    Keywords: Geophysics
    Type: Physica Scripta
    Format: text
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    NASA TECHNICAL REPORTS
  • 2
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    Dual-Peak Solar Cycle Distribution of Intense Solar and Geomagnetic Activity (1993)
    In:  Other Sources
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    Publication Date: 2018-06-08
    Keywords: Geophysics
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    NASA TECHNICAL REPORTS
  • 3
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    Do Coronal Holes Cause 27 Day Recurring Geomagnetic Storms? (1994)
    In:  Other Sources
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    Publication Date: 2018-06-08
    Description: We examine 3 years of interplanetary data and geomagnetic activity indices (1973-1975) to determine the causes of geomagnetic storms and substorms during the descending phase of the solar cycle. In this paper, we specifically studied the year 1974 where two long lasting coronating streams existed.
    Keywords: Geophysics
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    NASA TECHNICAL REPORTS
  • 4
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    Coronal Holes and 27-Day Recurring Magnetic Storms? (1994)
    In:  Other Sources
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    Publication Date: 2018-06-08
    Keywords: Geophysics
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    NASA TECHNICAL REPORTS
  • 5
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    Coronal Hole-Active Region-Current Sheet (CHARCS) Association with Intense Interplanetary and Geomagnetic Activity (1996)
    In:  Other Sources
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    Publication Date: 2018-06-08
    Description: Intense geomagnetic storms (Dst〈or equal to -100nT) have been associated with interplanetary structures involving large-intensity (B(sub 3)〈or equal to 10nT) and long-duration (T〈 or equal to 3 hours) values of the southward component of the IMF. We show that near solar maximum, the solar origin of such structures seems to be associated with active regions(flares and/or filament eruptions) ocurring close to the streamer belt and to growing low altitude coronal holes. It is also shown that such type of coronal holes had a dual-peak solar cycle distribution during solar cycle 21, similar to that previously reported for the above mentioned interplanetary and geomagnetic phenomena.
    Keywords: Geophysics
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    NASA TECHNICAL REPORTS
  • 6
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    Interplanetary Origin of Geomagnetic Activity in the Declining Phase of the Solar Cycle (1995)
    In:  Other Sources
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    Publication Date: 2018-06-08
    Description: Interplanetary magnetic field and plasma data are compared with ground-based geomagnetic Dst and AE indices to determine the causes of magnetic storms, substorms, and quiet during the descending phase of the solar cycle. The primary focus is on 1974 data characterized by the presence of two long-lasting corotating streams associated with coronal holes.
    Keywords: Geophysics
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    NASA TECHNICAL REPORTS
  • 7
    Electronic Resource
    Electronic Resource
    Epidermal growth factor induces the accumulation of calpactin II on the cell surface during membrane ruffling (1990)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 15 (1990), S. 34-40 
    Details
    ISSN: 0886-1544
    Keywords: rat liver cells ; immunoprecipitation ; immunocytochemistry ; membrane-bound proteins ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Confluent and proliferatively quiescent T51B rat liver epithelial cells provide a cellular model for the study of epidermal growth factor (EGF) effects in non-neoplastic cells. Immunoreactive calpactin II, a well-known substrate for EGF-receptor kinase, was found predominantly in the cytosol, although a second im-munoreactive pool was found in a Triton X-100-extractable membrane fraction. Stimulation with EGF resulted in a rapid and transient (2-;5 min) formation of ruffles at the cell surface and at the cell-cell contacts. Both calpactin II and filamentous actin were found co-localized at the membrane ruffles. Immunopre-cipitations of membrane-bound calpactin II from 32P-labeled cells indicate a transient EGF-dependent phosphorylation of calpactin II correlating with membrane ruffling. These results suggest a temporal (2-5 min) function for calpactin II at the plasma membrane during the EGF-induced mitogenesis of T51B cells.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cm.970150106
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  • 8
    Electronic Resource
    Electronic Resource
    In vitro migration of Hydra nematocytes: The influence of the natural extracellular matrix (the mesoglea), of collagen type IV and type I, laminin, and fibronectin on cell attachment, migration parameters, and on patterns of cytoskeletal proteins (1991)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 20 (1991), S. 215-227 
    Details
    ISSN: 0886-1544
    Keywords: cell migration ; extracellular matrix ; cytoskeleton ; nematocytes ; Hydra ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: We have established an in vitro migration system for nematocytes of the fresh water cnidarian Hydra. Nematocytes display a migratory behavior on isolated sheets of the naturally occurring extracellular matrix, the mesoglea, as well as on surfaces coated with collagen type IV or laminin. Cell behavior was analyzed using video microscopic techniques. Average migration speeds of nematocytes on the mesoglea (140 μm/hr) were lower than values reported from in vivo studies (500 μm/hr). Cells on collagen IV moved at about the same average speed (115 μm/hr) as nematocytes on the natural extracellular matrix; those on laminin were considerably slower (20 μm/hr). Attachment but no movement of cells was found on glass or on surfaces coated with collagen type I and fibronectin. In addition to the differential migration speeds, nematocytes displayed distinct morphologies depending on the substratum. In order to elucidate the causes of the observed cell shape and behavior modulations induced by the offered substratum, the arrangement of major cytoskeletal proteins in Hydra nematocytes during the in vitro migration or attachment was investigated. The pattern of F-actin, myosin, and tubulin was determined by immunocytochemical techniques and confocal laser scanning microscopy in nematocytes moving on the mesoglea, on collagen IV, and on laminin, or in cells attaching to fibronectin. We found that the distribution of the cytoskeletal proteins was strikingly different in moving and in stationary cells. The patterns of cytoskeletal proteins in all nematocytes moving on the different substrata, however, was quite similar.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cm.970200305
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  • 9
    Electronic Resource
    Electronic Resource
    Overexpression of an epitope- tagged β-tubulin in Chinese hamster ovary cells causes an increase in endogenous α-tubulin synthesis (1995)
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 31 (1995), S. 259-272 
    Details
    ISSN: 0886-1544
    Keywords: microtubules ; transfection ; hemagglutinin antigen ; autoregulation ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A Chinese hamster β-tubulin cDNA, engineered to express a 9 amino acid epitope from the influenza hemagglutinin antigen (HA), was transfected into Chinese hamster ovary (CHO) cells. The recombinant protein (HAβ1-tubulin) appeared to behave normally by the following criteria: immunofluorescence indicated that HAβ1-tubulin incorporated into all classes of interphase and spindle microtubules as well as microtubule organizing centers. The sensitivity of the cells expressing HAβ1-tubulin to Colcemid and taxol was unchanged. A 210 kD microtubule associated protein (MAP) remained associated with microtubules that incorporate HAβ1-tubulin. The synthesis of both endogenous β-tubulin and HAβ1-tubulin was repressed by colchicine. The HAβ1-tubulin incorporated into microtubules to the same extent as the endogenous β-tubulin, and the overall extent of microtubule assembly in transfected cells was unchanged. Finally, trasfected cells had normal growth rates and morphologies. When effects on endogenous tubulin production were measured, it was found that expression of the HAβ1-tubulin reduced the synthesis of endogenous wild-type β-tubulin but increased the synthesis of α-tubulin. At steady state, a small increase in total tubulin consistent with the increased synthesis of α-tubulin was found. The results indicate that expression of excess exogenous β-tubulin perturbs the synthesis of endogenous α-tubulin in a manner that is not easily explained by current models of tubulin regulation. The changes in tubulin synthesis along with degradation of excess tubulin subunits may reflect mechanisms that exist to ensure coordinate levels of α- and β-tubulin for assembly. © 1995 Wiley-Liss, Inc.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cm.970310403
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  • 10
    Electronic Resource
    Electronic Resource
    Role of amino acid-induced changes in ion fluxes in the regulation of hepatic protein synthesis (1995)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 163 (1995), S. 277-284 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Alanine is a powerful stimulator of hepatic protein synthesis whose mechanism of action has not yet been ascertained. The present work aimed to elucidate whether rate changes in ion fluxes accompanying the transport of this amino acid could play a role in the stimulation of protein synthesis. In perfused livers, the utilization of alanine produced a net uptake of K+ of 1.5 μMol/min/liver, a progressively increasing efflux of Ca2+ to reach a maximum of 0.9 μMol/min/liver, and alkalization of the extracellular medium. Inhibition of Na+/K+ exchange by ouabain reversed only the uptake of K+, indicating that this is the main way for the efflux of Na+ cotransported with alanine. In isolated hepatocytes, the uptake of alanine increased the intracellular content of K+ and the cell volume. The following observations suggest that these changes, and not an increased intracellular concentration of Na+, are associated with the stimulation of protein synthesis: 1) Ouabain inhibited the alanine stimulation of L-[3H]-valine incorporation into protein without altering the basal rate of protein labeling; 2) ouabain had no effects on alanine uptake indicating that Na+ influx is not involved in the alanine stimulation of protein synthesis; 3) disruption of Na+ gradient across the plasma membrane by specific ionophores, monensin and gramicidin D, inhibited both basal and alanine-stimulated protein synthesis, but substitution of extracellular Na+ by K+ did not prevent the stimulatory action of alanine. The observation that hypotonic buffer enhanced protein synthesis to the same degree than alanine in liver cells indicates that alanine-induced cell swelling could be sufficient to stimulate protein synthesis. © 1995 Wiley-Liss, Inc.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1041630208
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