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  • Life Sciences (General)  (4)
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  • 1
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    Fatal Saccharomyces Cerevisiae Aortic Graft Infection (2002)
    In:  Other Sources
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    Publication Date: 2019-07-13
    Description: Saccharomyces cerevisiae is a yeast commonly used in baking and a frequent colonizer of human mucosal surfaces. It is considered relatively nonpathogenic in immunocompetent adults. We present a case of S. cerevisiae fungemia and aortic graft infection in an immunocompetent adult. This is the first reported case of S. cerevisiue fungemia where the identity of the pathogen was confirmed by rRNA sequencing.
    Keywords: Life Sciences (General)
    Type: Journal of Clinical Microbiology (ISSN 0095-1137); 40; 7; 2691-2692
    Format: text
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    NASA TECHNICAL REPORTS
  • 2
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    The Grand Assault (2003)
    In:  Other Sources
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    Publication Date: 2019-07-10
    Description: Plasmodium falciparum, the protozoan parasite responsible for most human malaria, is among the most studied pathogens of all time, probably only exceeded by the human immunodeficiency virus HTV and the bacterium Mycobacterium tuberculosis. The extent of human suffering and the devastating costs of malaria have long been recognized by world bodies, and numerous initiatives have been taken over the years in an effort to defeat this insidious microbe. Beginning in 1996, an international consortium of scientists from more than a dozen institutions set about to determine the sequence of the organism's 23-megabase genome. Their massive effort-which ended up going well beyond simple sequencing is reported in this special issue of Nature. The avowed goal of the project was to search for chinks in the parasite's armor so that new and effective drugs and vaccines might be developed.
    Keywords: Life Sciences (General)
    Type: Nature News and Views: Special Malaria Issue
    Format: text
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    NASA TECHNICAL REPORTS
  • 3
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    Process and apparatus for analyzing specimens for the presence of microorganisms therein (1980)
    In:  CASI
    Details
    Publication Date: 2019-08-15
    Description: Microorganisms in a specimen are detected, identified, and enumerated by introducing the specimen into a sampling cartridge and diluting the specimen with a known volume of water within the cartridge. The cartridge has a manifold and several cassettes attached to the manifold. Each cassette contains a serpentine flow channel having a series of filters therein and a detection cell located downstream from each filter. The flow channel in each cassette also contains a culture medium which is freeze dried and is highly selective in the sense that it promotes the growth of one type of microorganism, but not others. The mixture of the specimen and water flows from the manifold into the flow channel of each cassette where it rehydrates the culture medium therein and further flows through the filters. Each filter removes a known proportion of the microorganisms from the mixture of specimen, water and medium, thereby effecting a serial dilution. After the cassettes are heated to incubate the microoganisms, the detection cells are observed for growth of the microorganisms therein which is manifested in a change in the light transmitting characteristics of the mixtures within the cells.
    Keywords: Life Sciences (General)
    Format: application/pdf
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  • 4
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    Emergence of RNA and Early Life; Experimental Modeling and Geochemical Constraints (2002)
    In:  CASI
    Details
    Publication Date: 2019-07-13
    Description: Support from this grant continues to fund our research on two related problems. One involves attempts to model the abiotic formation of simple source compounds for functional biomolecules, their concentration from dilute state in the hydrosphere and in several cases surface induced reactions to form precursor monomers for bioactive end products. The second area is a search for the earliest traces of life on Earth and the early environments on Earth and Mars. For this purpose we have analyzed the isotopic compositions of carbon and nitrogen in graphitic residues that have been thought to represent the remains of microorganisms. The results of these studies have been presented in a number of publication, listed as references.
    Keywords: Life Sciences (General)
    Type: Rept-99-1436R1
    Format: text
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