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  • 1
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    Hematological measurements in rats flown on Spacelab shuttle, SL-3 (1987)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: Previous studies have shown that a decrease in red cell mass occurs in astronauts, and some studies indicate a leukocytosis occurs. A life science module housing young and mature rats was flown on shuttle mission Spacelab 3 (SL-3), and the results of hematology studies of flight and control rats are presented. Statistically significant increases in the hematocrit, red blood cell counts, and hemoglobin determinations, together with a mild neutrophilia and lymphopenia, were found in flight animals. No significant changes were found in bone marrow and spleen cell differentials or erythropoietin determinations. Clonal assays demonstrated an increased erythroid colony formation of flight animal bone marrow cells at erythropoietin doses of 0.02 and 1.0 U/ml but not 0.20 U/ml. These results agree with some but vary from other previously published studies. Erythropoietin assays and clonal studies were performed for the first time.
    Keywords: Life Sciences (General)
    Type: The American journal of physiology (ISSN 0002-9513); Volume 252; 2 Pt 2; R216-21
    Format: text
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    NASA TECHNICAL REPORTS
  • 2
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    Effects of spaceflight on rat peripheral blood leukocytes and bone marrow progenitor cells (1996)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: The white blood cell (WBC) elements and the bone marrow myeloid progenitor cell populations were analyzed to ascertain adaptation to micro-gravity and subsequent readaptation to 1 G in rats flown on the 14-day Spacelab Life Sciences-2 (SLS-2) mission. Bone marrow cells were harvested from one group of rats killed inflight (FD13) and blood was drawn from three other groups at various times. The WBC level was normal on FD14 with the exception of neutrophilia. On FD13, numbers of colony-forming units-granulocyte (CFU-G), CFU-GM, and CFU-M from flight animals were decreased compared with ground controls when incubated with recombinant rat interleukin-3 (rrIL-3) alone or in combination with recombinant human erythropoietin (rhEpo). On recovery (R + 0), flight rats had decreased numbers of total leukocytes and absolute numbers of lymphocytes and monocytes with elevated neutrophils compared with control rats. They had lower numbers of CD4, CD8, CD2, CD3, and B cells in the peripheral blood but no differences in spleen lymphocytes.
    Keywords: Life Sciences (General)
    Type: Journal of leukocyte biology (ISSN 0741-5400); Volume 60; 1; 37-43
    Format: text
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    NASA TECHNICAL REPORTS
  • 3
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    Design, development, and field testing of Infrared Heterodyne Radiometer (IHR) for remote profiling of tropospheric and stratospheric species (1981)
    In:  CASI
    Details
    Publication Date: 2019-06-28
    Description: The performance of a dual-channel infrared heterodyne radiometer, designed to remotely monitor the concentration and vertical distribution of selected atmospheric species, is described. Ground based solar viewing measurement using the IHR were performed at selected laser transitions for ammonia (NH3 and ozone O3). Flight tests were conducted aboard the Galileo II, NASA Ames CV-990, on the Latitude Survey Mission. Ozone was the selected atmospheric species for the airborne flight measurements because of the scientific interest in this atmospheric species, the availability of in situ monitors, the coordinated ozone measurements, and the availability of ground truth data. The IHS was operated in the solar viewing mode to determine ozone distributions in the stratosphere and in the nadir viewing mode to determine the ozone distribution in the troposphere. Airborne atmospheric propagation measurements also were carried out at selected CO2 laser transitions.
    Keywords: ENVIRONMENT POLLUTION
    Type: NASA-CR-3448 , A610-IV
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 4
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    Infrared heterodyne spectrometer measurements of vertical profile of tropospheric ammonia and ozone (1977)
    In:  Other Sources
    Details
    Publication Date: 2019-07-13
    Description: Remote sensing of the concentration and vertical distribution of atmospheric gases has been carried out using a dual CO2 laser multichannel infrared heterodyne spectrometer (IHS). The high specificity and nearly quantum-noise-limited sensitivity of the IHS provide the capability of scanning individual signature lines of selected atmospheric constituents in the 9 to 11 micron region. A comprehensive investigation of the spectral overlap between CO2 laser local oscillator transitions and selected atmospheric constituents was performed; measurements of the atmospheric absorption of solar radiation from the ground were carried out at selected laser transitions for ammonia and ozone.
    Keywords: ENVIRONMENT POLLUTION
    Type: AIAA PAPER 77-73 , Aerospace Sciences Meeting; Jan 24, 1977 - Jan 26, 1977; Los Angeles, CA
    Format: text
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    NASA TECHNICAL REPORTS
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