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  • 1
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 2 (1974), S. 337-348 
    ISSN: 0091-7419
    Keywords: Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Satellite phage P4 causes the head proteins of a helper phage, such as P2, to form a small head. This small head is never found in cells infected by the helper virus alone. This finding, coupled with the dominance of P4 over its helper, indicates that the P4 genome has the potential for specific head size determination. Satellite phage P4 codes for a late protein which is found in the P4 head (45 copies/head). This protein may determine head size. Our finding that the small size of P4 DNA does not determine small head size in an in vitro DNA packaging system lends further support to the idea that a P4 protein determines small head size.Formation of P2 headlike structures is accompanied by cleavage of P2 head proteins. Cleavage of the major head protein precursor can be observed in vitro after lysis of infected cells with lysozyme. The rate of this in vitro reaction is not affected by deoxyribonuclease; thus there cannot be a tight coupling between DNA packaging and the cleavage of the major capsid protein.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 12 (1979), S. 467-470 
    ISSN: 0091-7419
    Keywords: epidermal growth factor ; fibroblast growth factor ; cell division ; mitogenesis ; growth control ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: The enhanced ability of murine serum to support growth of 3T3 cells, when compared with fetal calf serum, is also evident on variants of 3T3 cells lacking the ability to bind epidermal growth factor (EGF). Variant 3T3 cell lines unable to bind EGF also retain a mitogenic response to fibroblast growth factor.
    Additional Material: 1 Ill.
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  • 3
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 8 (1978), S. 263-268 
    ISSN: 0091-7419
    Keywords: insulin ; mitogenesis ; epidermal growth factor ; fibroblast growth factor ; prostaglandin F2α ; phorbol myristate acetate ; Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: The growth-promoting activities of fetal bovine serum, cortisol, phorbol myristate acetate, prostaglandin F2α, insulin, epidermal growth factor, and fibroblast growth factor were evaluated on four murine embryo cell lines (Swiss 3T3, Balb 3T3, M2, and C3H10T1/2). Each cell had an unique response spectrum to this collection of reported mitogens. Phorbol myristate acetate and prostaglandin F2α were active only on selected cell lines; cortisol was inactive on all four lines. Serum, epidermal growth factor, and fibroblast growth factor were able to stimulate cell division in all four lines, albeit to varying degrees for the different target cells.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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