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Effect of space flight on bone strength (1982)

Spengler, D. M. ; Morey, E. R. ; Carter, D. R. ; [et al.]

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Publication Date: 2011-08-18

Description: To test the possibility that spaceflight has a deleterious effect on bone mechanical properties, femur breaking strength by torsional loading in rats that had been flown for 19 days aboard Cosmos 936 was determined. The results showed that femurs from flight rats were less stiff than the flight controls, and failed under torsion at a lower torque and energy of absorption. The defect was corrected following space flight and could be prevented during space flight by centrifuging the rats at 1 x g. Altered bone geometry due to inhibition of bone formation at the periosteal surface provides the most likely explanation for the decrease in bone strength during spaceflight.

Keywords: LIFE SCIENCES (GENERAL)

Type: p. S-75

Format: text

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