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  • Analytical Chemistry and Spectroscopy  (3)
  • Immunohistochemistry  (2)
  • 1985-1989  (5)
  • 1
    Electronic Resource
    Electronic Resource
    Glucagon-related peptides in the rat hypothalamus (1986)
    Springer
    Cell & tissue research 246 (1986), S. 71-75 
    Details
    ISSN: 1432-0878
    Keywords: Glucagon-related peptides ; Rat hypothalamus ; Radioimmunochemistry ; Immunohistochemistry ; Food deprivation ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Immunohistochemically, nerve fibers and terminals reacting with anti-N-terminal-specific but not with anti-C-terminal-specific glucagon antiserum were observed in the following rat hypothalamic regions: paraventricular nucleus, supraoptic nucleus, anterior hypothalamus, arcuate nucleus, ventromedial hypothalamic nucleus and median eminence. Few fibers and terminals were demonstrated in the lateral hypothalamic area and dorsomedial hypothalamic nucleus. Radioimmunoassay data indicated that the concentration of gut glucagon-like immunoreactivity was higher in the ventromedial nucleus than in the lateral hypothalamic area. In food-deprived conditions, this concentration increased in both these parts. This was also verified in immunostained preparations in which a marked enhancement of gut glucagon-like immunoreactivity-containing fibers and terminals was observed in many hypothalamic regions. Several immunoreactive cell bodies were found in the ventromedial and arcuate nuclei of starved rats. Both biochemical and morphological data suggest that glucagon-related peptides may act as neurotransmitters or neuromodulators in the hypothalamus and may be involved in the central regulatory mechanism related to feeding behavior and energy metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00219001
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Structural investigation of the antibiotic sporaviridin: 11 - Molecular secondary ion mass spectral studies on the constituent pentasaccharides viridopentaosesFor Part 10 see K.-I. Harada, I. Kimura, E. Takami and M. Suzuki, J. Antibiotics 37, 976 (1984). (1985)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 20 (1985), S. 582-588 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Molecular secondary ion mass spectra of three pentasaccharides, viridopentaoses A, B and C, using various matrices, are discussed. The appearance of the molecular ion species is dependent upon the relative proton affinities between the sample and the organic matrix material. However, the presence of sodium ion, rather than proton, also greatly influences the appearance of the molecular ion species. The glycosidic linkages are mainly cleaved between the glycosidic oxygen atom and the anomeric carbon atom to give informative sugar sequence ions. These fragmentations have been confirmed by the linked scanning technique (B/E).
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210200910
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  • 3
    Electronic Resource
    Electronic Resource
    Raman spectra of halogen-substituted methanes in the liquid state. 3For Part 2, see Ref. 2. - Temperature effects (1987)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 18 (1987), S. 47-52 
    Details
    ISSN: 0377-0486
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The effect of temperature on the peak positions, the isotropic and reorientational band widths and the depolarization ratios of the Raman bands for the totally symmetric vibrations of CHCl3, CH2Cl2, CH2Br2, CH3Br, CH3I and CD3I has been measured in the liquid state. The isotropic band width for a C—X stretching vibration decreases with increasing temperature for molecule with only one C—X bond, whereas it increases for a molecule with two or three equivalent C—X bonds. The isotropic band width for the deformation vibrations decreases with increase in temperature. For all the bands, the depolarization ratios depend only slightly on temperature.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jrs.1250180109
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  • 4
    Electronic Resource
    Electronic Resource
    Isotropic Raman band shape and vibrational relaxation for molecules in the liquid state: A Critical study of some band shape functions (1985)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 16 (1985), S. 377-385 
    Details
    ISSN: 0377-0486
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: A band shape function for the isotropic Raman scattering described in terms of the band width in the weak coupling limit and the relaxation time of the bath mode has been proposed by summing the results of Berne et al. [J. Chem. Phys. 45, 1086 (1966)], Wang [Mol. Phys. 33, 207 (1977)] and Knauss [Mol. Phys. 36, 413 (1978)]. The results of band analyses with this function have been compared with those obtained from other conventionally used band shape and correlation functions. The present function is preferable for precise interpretation of vibrational relaxation mechanisms, particularly for those cases where temperature and concentration dependence of the band parameters are involved.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jrs.1250160606
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  • 5
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    Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo (1988)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1988-01-15
    Description: A crucial question in the study of immunological reactions in the central nervous system (CNS) concerns the identity of the parenchymal cells that function as the antigen-presenting cells in that organ. Rat bone marrow chimeras and encephalitogenic, major histocompatability--restricted T-helper lymphocytes were used to show that a subset of endogenous CNS cells, commonly termed "perivascular microglial cells," is bone marrow-derived. In addition, these perivascular cells are fully competent to present antigen to lymphocytes in an appropriately restricted manner. These findings are important for bone marrow transplantation and for neuroimmunological diseases such as multiple sclerosis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hickey, W F -- Kimura, H -- KO7-NS0087/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1988 Jan 15;239(4837):290-2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104-6079.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3276004" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antigen-Presenting Cells/*immunology ; Astrocytes/immunology ; Bone Marrow/*immunology ; Bone Marrow Transplantation ; Central Nervous System/blood supply/*immunology/pathology ; Chimera ; Encephalomyelitis, Autoimmune, Experimental/immunology/pathology ; Endothelium/immunology ; Graft vs Host Disease/immunology ; Histocompatibility Antigens/analysis/immunology ; Immunohistochemistry ; Multiple Sclerosis/immunology/pathology ; Neuroglia/*immunology ; Rats ; Rats, Inbred Lew ; T-Lymphocytes/immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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