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  • 1
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 3 (1980), S. 507-515 
    ISSN: 0935-6304
    Keywords: Constant volume Varigrad ; Hydrostatic Varigrad ; Incremental method of gradient elution ; Modified incremental method, advantages of Poisson distribution ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Different methods for producing a pre-assigned gradient in liquid chromatography are presented. A systematic approach to the calculations involved is given. The derived equations are mostly Poisson and Poisson summation distributions which are tabulated in the literature. The incremental method of gradient elution developed by Scott has been modified. In the modified apparatus two mixing chambers are used instead of one. This leads to an appreciable decrease in the number of reservoirs needed for the same precision in fitting a desired gradient. The application of the derived equations, together with other Varigrad modifications, will be given in Part 2 of this paper (to be published shortly in this Journal).
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 3 (1980), S. 575-582 
    ISSN: 0935-6304
    Keywords: Numerical examples ; Constant volume Varigrad ; Hydrostatic Varigrad ; Incremental method of gradient elution ; Modified incremental method ; Non-homogeneous Varigrad ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Part 2 deals with the application of the equations derived in Part 1 to the systematic calculations of the constant volume and hydrostatic Varigrads. Examples are given which illustrate the advantage of using the modified incremental method of gradient elution. The non-homogeneous Varigrad, where mixing chambers may vary in volume, is also treated.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Publication Date: 1980-12-12
    Description: Vasoactive intestinal peptide, a smooth-muscle relaxant neuropeptide with neurotransmitter properties, was relaxed during electrical field stimulation of guinea pig trachea. The amount released correlated with the degree of relaxation, and the release was blocked by tetrodotoxin. Prior incubation of the trachea with antiserum to vasoactive intestinal peptide reduced the relaxation. Thus vasoactive intestinal peptide may mediate the nonadrenergic relaxation of tracheal smooth muscle.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Matsuzaki, Y -- Hamasaki, Y -- Said, S I -- HL-14187/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1980 Dec 12;210(4475):1252-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6254154" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenergic Fibers/*physiology ; Animals ; Antigen-Antibody Reactions ; Electric Stimulation ; Female ; Gastrointestinal Hormones/*physiology ; Humans ; Mice ; *Muscle Contraction ; *Muscle Relaxation ; Muscle, Smooth/drug effects ; Neural Inhibition ; Synaptic Transmission ; Tetrodotoxin/pharmacology ; Trachea/*innervation ; Vasoactive Intestinal Peptide/immunology/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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