ISSN:
0935-6304
Keywords:
Capillary gas chromatography
;
FID, O-FID, and MS detection
;
Glycol ethers and glycol ether acetates
;
Heptafluorobutyryl derivatives
;
Mass spectra
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Twelve compounds, commonly used as industrial solvents and belonging to the chemical class of glycol ethers and glycol ether acetates, were investigated. Several analytical conditions, applied to single or connected capillary columns of different length and polarity coating and connected to FID, O-FID and MS detection systems, were assayed. Tests on heptafluorobutyryl derivatives were also attempted to improve the analytical sensitivity. The aims were to establish gas chromatographic methods suitable for analysis of reference standard compounds and to verify their applicability to biological matrix analysis for pharmacokinetic and toxicological studies, since these chemicals have been shown to be hazardous in laboratory animals and are presumed to be dangerous in man.
Additional Material:
6 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jhrc.1240190705
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