ISSN:
1432-1041
Keywords:
antipyrine clearance
;
apolipoproteins
;
HDL
;
A-I
;
A-II
;
B
;
HDL2 cholesterol
;
microsomal enzyme induction
;
phenobarbital
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary Serum high density lipoprotein (HDL) subfractions HDL2 and HDL3, apolipoproteins, and plasma antipyrine clearance (AP-CL) rate, an index of liver microsomal enzyme activity, were determined in 21 healthy subjects. High HDL cholesterol and HDL2 cholesterol concentrations and HDL cholesterol/cholesterol and HDL2/HDL3 cholesterol ratios were associated with high AP-CL. Phenobarbital enhanced antipyrine elimination and increased the apolipoprotein A-I/A-II ratio. Subjects who had high AP-CL had a more antiatherogenic HDL subfraction and apolipoprotein profile than those with low AP-CL.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00278594
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