ISSN:
1432-072X
Keywords:
Growth inhibition
;
Threonine
;
Isoleucinevaline biosynthesis
;
Euglena gracilis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract InEuglena gracilis the growth inhibition by threonine was accompanied by a rapid accumulation of isoleucine in the cells. Among threonine-catabolizing enzymes only threonine dehydratase was detected in high activity inEuglena, and 2-oxobutyrate, the dehydratase products of threonine, also inhibited as did threonine. Threonine dehydratase was located in the cytosol, and its activity was not affected by isoleucine and related amino acids. 2-Oxobutyrate strongly inhibited the synthesis of valine from pyruvate while augmented the synthesis of isoleucine in mitochondria.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00690811
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