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  • 1
    Electronic Resource
    Electronic Resource
    Isolation and Structure of a GM3-Type Ganglioside Molecular Species (1999)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1999 (1999), S. 765-769 
    Details
    ISSN: 1434-193X
    Keywords: Glycosphingolipids ; Ganglioside ; GM3 ; Starfish ; Luidia maculata ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: -A ganglioside molecular species, LMG-2 (1), has been obtained from the water-soluble lipid fraction of the chloroform/methanol extract of the starfish Luidia maculata. On the basis of chemical and spectroscopic findings, the structure of 1 has been elucidated. 1 is a ganglioside molecular species of starfish resembling the mammalian ganglioside GM3. In addition, 1 shows neuritogenic activity toward the rat pheochromocytoma cell line PC-12 cell.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Isolation and Structure of a New Ganglioside Molecular Species (1999)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1999 (1999), S. 771-774 
    Details
    ISSN: 1434-193X
    Keywords: Natural products ; Glycosphingolipids ; Gangliosides ; Starfish ; Linckialaevigata ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: -A ganglioside molecular species [LLG-3 (1)] has been obtained from the water-soluble lipid fraction of the CHCl3/MeOH extract of the starfish Linckialaevigata. On the basis of chemical and spectroscopic findings, the structure of 1 has been elucidated. Negative-ion FABMS provided important information concerning both the structure of the sugar moiety and the molecular mass of the ganglioside. On the other hand, positive-ion FABMS/MS of [M + Na]+ ions obtained in the positive-ion FABMS of the ceramide lactoside (4) derived from 1 indicated the structure of the fatty acid chain of the ceramide moiety. 1 represents a new ganglioside molecular species possessing a 2→11-linked tandem-type disialosyl moiety.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Isolation and Structure of Biologically Active Gangliosides from the Sea Cucumber Holothuria pervicax (1998)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1998 (1998), S. 2519-2525 
    Details
    ISSN: 1434-193X
    Keywords: Glycosphingolipids ; Gangliosides ; Sea cucumber ; Holothuria pervicax ; Neuritogenic activity ; Natural products ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Three ganglioside molecular species, HPG-8, HPG-3, and HPG-1, have been obtained from the polar fraction of the chloroform/methanol extract of the sea cucumber Holothuriapervicax. The structures of these gangliosides have been determined on the basis of chemical and spectroscopic evidence. They represent new ganglioside molecular species. HPG-8 is a sulfated monosialo-ganglioside, while HPG-3 and HPG-1 are disialo-gangliosides possessing 2→4-linked tandem-type disialosyl moieties. These three gangliosides qualitative neuritogenic activity toward the rat pheochromocytoma cell line, PC-12 cells.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Biologically Active Glycosides from Asteroidea, 37. Glycosphingolipids from the Starfish Luidia maculata, 1 Structure of A New Sulfatide Molecular Species (1997)
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 1997 (1997), S. 1797-1800 
    Details
    ISSN: 0947-3440
    Keywords: Glycosphingolipids ; Sulfatide ; Starfish ; Luidia maculata ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A sulfatide molecular species [LMG-1 (1)] have been obtained from the water soluble lipid fraction of the chloroform/methanol extract of the starfish Luidia maculata. On the basis of chemical and spectroscopic findings, the structure of 1 has been elucidated. Negative FAB mass spectrometry provided important information both on the structure of the sugar moiety and on the molecular mass of the sulfatide. 1 is, to the authors' knowledge, new sulfatide molecular species and first sulfatide obtained from starfish. In addition, 1 shows neuritogenic activity toward the rat pheochromocytoma cell line, PC-12 cell.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jlac.199719970826
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