Publication Date:
2002-05-04
Description:
The history of life on Earth is chronicled in the geological strata, the fossil record, and the genomes of contemporary organisms. When examined together, these records help identify metabolic and regulatory pathways, annotate protein sequences, and identify animal models to develop new drugs, among other features of scientific and biomedical interest. Together, planetary analysis of genome and proteome databases is providing an enhanced understanding of how life interacts with the biosphere and adapts to global change.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Benner, Steven A -- Caraco, M Daniel -- Thomson, J Michael -- Gaucher, Eric A -- GM 54075/GM/NIGMS NIH HHS/ -- R01 GM054075/GM/NIGMS NIH HHS/ -- R01 GM054075-02/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2002 May 3;296(5569):864-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry, University of Florida, Gainesville FL, 32611-7200, USA. benner@chem.ufl.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11988562" target="_blank"〉PubMed〈/a〉
Keywords:
Amino Acid Sequence
;
Amino Acid Substitution
;
Animals
;
Codon
;
Databases, Genetic
;
Earth (Planet)
;
*Evolution, Molecular
;
*Fossils
;
Gene Duplication
;
*Genome
;
Geological Phenomena
;
*Geology
;
Humans
;
*Life
;
Paleontology
;
Pharmacology
;
Proteins/chemistry/physiology
;
*Proteome
;
Research
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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