ISSN:
0947-3440
Keywords:
α-Amino acids
;
Teoc-protected α-trifluoromethyl-substituted
;
Fmoc amino acid fluorides
;
Peptidomimetics
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A new method for peptide coupling, involving α-trifluoromethyl substituted amino acids as nucleophiles, proceeds via fluoride catalyzed in situ deprotection and coupling of N-Teoc protected amino acid esters. A mixed anhydride is thought to be the reaction intermediate.
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199719971219
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