Publication Date:
1995-10-27
Description:
Near-field scanning optical microscopy of phospholipid monolayers doped with fluorescent lipid analogs reveals previously undescribed features in various phases, including a concentration gradient at the liquid-expanded/liquid-condensed domain boundary and weblike structures in the solid-condensed phase. Presumably, the web structures are grain boundaries between crystalline solid lipid. These structures are strongly modulated by the addition of low concentrations of cholesterol and ganglioside GM1 in the monolayer.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hwang, J -- Tamm, L K -- Bohm -- Ramalingam, T S -- Betzig, E -- Edidin, M -- AI14584/AI/NIAID NIH HHS/ -- AI30557/AI/NIAID NIH HHS/ -- DK44375/DK/NIDDK NIH HHS/ -- R37 AI030557/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1995 Oct 27;270(5236):610-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7570018" target="_blank"〉PubMed〈/a〉
Keywords:
1,2-Dipalmitoylphosphatidylcholine/*chemistry
;
Boron Compounds
;
Cholesterol/*chemistry
;
Fluorescent Dyes
;
G(M1) Ganglioside/*chemistry
;
Microscopy/*methods
;
Microscopy, Fluorescence
;
Phosphatidylcholines
;
Phospholipids/*chemistry
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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