ISSN:
0749-1581
Keywords:
Fully 1H-1H decoupled 2D shift correlation spectroscopy
;
Explanation of anomalous artifact intensity
;
COLOC and HETRES experiments
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Two-dimensional heteronuclear chemical shift correlation experiments which attempt decoupling in f1 have been shown to give artifacts in strongly coupled systems. In particular, COLOC and HETRES experiments on methylene groups show an artifact midway between the two proton lines. This paper provides an explanation of the artifact intensity behaviour with respect to the strength of coupling between the methylene protons. Experimental results on 1,2-dibromoethylbenzene are presented, and theoretical calculations were carried out on the COLOC experiment and a mathematical model was developed which predicted the artifact appearance and intensity. Simulations were also performed using the simulation program SIMPLTN to verify the experimental and theoretical results.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260290406
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