Electronic Resource
Springer
Theoretical and applied genetics
50 (1977), S. 163-172
ISSN:
1432-2242
Keywords:
Biases
;
Drift
;
Inequality of Gene Effects
;
Linkage Disequilibrium
;
Epistasis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary Bias in the estimation of gene number from a population of finite size will be reduced when the number of generations and the selection differential in the primary selection program are increased. A procedure to minimize bias due to dominance is proposed. Bias due to linkage disequilibrium is decreased by long generations of selection and small change of linkage disequilibrium. Bias due to inequality of gene effects was studied assuming that gene effects follow a half normal distribution. The epistatic bias arising from multiplicative gene effects disappears when the logarithms of the original measurements are considered even though the gene number estimate is unsatisfactory without transformation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00277737
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