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  • 1
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 21 (1985), S. 2201-2219 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A higher-order shear deformation theory is used to analyse laminated anisotropic composite plates for deflections, stresses, natural frequencies and buckling loads. The theory accounts for parabolic distribution of the transverse shear stresses, and requires no shear correction coefficients. A displacement finite element model of the theory is developed, and applications of the element to bending, Vibration and stability of laminated plates are discussed. The present solutions are compared with those obtained using the classical plate theory and the three-dimensional elasticity theory.
    Additional Material: 11 Ill.
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  • 2
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 21 (1985), S. 1853-1870 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The detailed stress analysis of the toroidal field superconducting coil is needed to ensure its structural integrity, which includes conductor breakage, insulation breakage, sliding between two turns, or support structure failure. Such detailed-analysis requires that each of the superconducting coil turns be modelled separately. In this paper, a curved beam finite element,13 having constant radius of curvature, is considered to model a turn of a noncircular toroidal field coil. Four different coil shapes subjected to electromagnetic body forces due to toroidal magnetic fields are analysed to assess the finite element models: circular, elliptic, Princeton-D8 and compound shape9. The comparison of analytical and finite element analysis results for resultant forces, tensions and displacements suggest that the proposed approach may be extended to the detailed stress analysis of the noncircular toroidal field superconducting coil.
    Additional Material: 9 Ill.
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  • 3
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 7 (1987), S. 1325-1342 
    ISSN: 0271-2091
    Keywords: Convective Heat Transfer ; Finite Elements ; Navier-Stokes Equations ; Numerical Results ; Penalty Model ; Staggered Cylinders ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The two-dimensional Navier-Stokes equations and the energy equation governing steady laminar incompressible flow are solved by a penalty finite-element model for flow across finite depth, five-row deep, staggered bundles of cylinders. Pitch to diameter ratios of 1·5 and 2·0 are considered for cylinders in equilateral triangular and square arrangements. Reynolds numbers studied range from 100 to 400, and a Prandtl number of 0·7 is used. Velocity vector fields, streamline patterns, vorticity, pressure and temperature contours, local and average Nusselt numbers, pressure and shear stress distributions around the cylinder walls and drag coefficients are presented. The results obtained agree well with available experimental and numerical data.
    Additional Material: 10 Ill.
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Communications in Applied Numerical Methods 5 (1989), S. 237-246 
    ISSN: 0748-8025
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: This paper presents a formulation of a cubic spline that fits the first derivatives of a function at mesh points and the function value and its second derivative at the beginning of the interval. Error bounds for the function and its first three derivatives are derived over the whole interval. This formulation can be applied, in particular, to quadratures.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 9 (1989), S. 541-555 
    ISSN: 0271-2091
    Keywords: Inverse finite elements ; Solidification ; Extrusion ; Metal casting ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The flow and solidification of planar jets are analysed by means of an efficient inverse isotherm finite element method. The method is based on a tessellation that is constructed by isotherms as characteristic co-ordinate lines transverse to the flow direction. Thus opposite sides of finite elements lie on isotherms. The method allows the simultaneous determination of the location of the isotherms with the primary unknowns, namely, the velocity, the pressure, the temperature and the location of the free surface. Thus the determination of the location of the solidification front (which is known to pose significant computational difficulties) is automatic. This facilitates the control of the location of the solidification front by controlling macroscopic variables such as the flow rate, the cooling rate and the capillary design. The location of the solidification may then be suitably chosen to influence the frozen-in orientation and structure in extrusion of high-performance materials such as composites and polymers, in continuous casting of metals and in growth of crystals.
    Additional Material: 8 Ill.
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  • 6
    Publication Date: 1985-06-28
    Description: The search for new congeners of the leading anticancer drug doxorubicin has led to an analog that is approximately 1000 times more potent, noncardiotoxic at therapeutic dose levels, and non-cross-resistant with doxorubicin. The new anthracycline, 3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin (MRA-CN), is produced by incorporation of the 3' amino group of doxorubicin in a new cyanomorpholinyl ring. The marked increase in potency was observed against human ovarian and breast carcinomas in vitro; it was not accompanied by an increase in cardiotoxicity in fetal mouse heart cultures. Doxorubicin and MRA-CN both produced typical cardiac ultrastructural and biochemical changes, but at equimolar concentrations. In addition, MRA-CN was not cross-resistant with doxorubicin in a variant of the human sarcoma cell line MES-SA selected for resistance to doxorubicin. Thus antitumor efficacy was dissociated from both cardiotoxicity and cross-resistance by this modification of anthracycline structure.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sikic, B I -- Ehsan, M N -- Harker, W G -- Friend, N F -- Brown, B W -- Newman, R A -- Hacker, M P -- Acton, E M -- CA 24543/CA/NCI NIH HHS/ -- CA 32250/CA/NCI NIH HHS/ -- CA 33303/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1985 Jun 28;228(4707):1544-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/4012308" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Antineoplastic Agents ; Breast Neoplasms/drug therapy ; Cell Line ; Chemical Phenomena ; Chemistry ; Dose-Response Relationship, Drug ; Doxorubicin/adverse effects/*analogs & derivatives/therapeutic use ; Female ; Heart/drug effects ; Humans ; Isoenzymes ; L-Lactate Dehydrogenase/analysis ; Mice ; Myocardium/enzymology ; Ovarian Neoplasms/drug therapy ; Pregnancy
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 28 (1989), S. 2275-2292 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A plate bending element based on the generalized laminate plate theory (GLPT) developed by the senior author is described and its accuracy is investigated by comparison with the exact solutions of the generalized plate theory and the 3D-elasticity theory. The element accounts for transverse shear deformation and layer-wise description of the inplane displacements of the laminate. The element has improved description of the inplane as well as the transverse deformation response. A method for the computation of interlaminar (transverse) stresses is also presented.
    Additional Material: 16 Ill.
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  • 8
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 26 (1988), S. 1843-1854 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Using the incremental equations of motion of a continuous medium and the total Lagrangian description, three different elements, i.e. degenerated shell element, 3-D continuum element and solid-shell transition element, are developed for the geometrically non-linear analysis of laminated composite structures. Compatibility and completeness requirements are stressed in modelling shell-type structures in order to assure the convergence of the finite element analysis. A number of laminated plate and shell examples are presented to demonstrate the validity and efficiency of various elements.
    Additional Material: 10 Ill.
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  • 9
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 28 (1989), S. 27-41 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Owing to the failure of the finite element analyst to employ a properly refined computational model, the accuracy of preliminary finite element computations is often low. Thus, it is useful to introduce a computational procedure for improving the results obtained from a preliminary finite element solution. Such a procedure is presented in this paper. In this procedure the solution error components are decomposed into two parts. One of the error components is assumed to have a long period variation. The other component is assumed to have a short period variation. Multiplicative and additive correction procedures are introduced to iteratively eliminate the two error components. The multiplicative and additive correction procedures are implemented using multi-level solution techniques.
    Additional Material: 14 Ill.
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  • 10
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 28 (1989), S. 1061-1076 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: A general finite element is derived for beams or beam-columns with or without a continuous Winkler type elastic foundation. The need to discretize members into shorter elements for convergence towards an ‘exact’ solution is eliminated by employing in the derivation of the element exact shape functions obtained from the equation of the elastic line. Inter-nodal values of deflections, bending moments and shear forces are obtained using the exact shape functions and trigonometric series. The effect of heavy compressive or tensile axial forces on bending stiffness is treated as a linear problem by considering the axial force as a constant parameter affecting the stiffness. FORTRAN subroutines to compute the stiffness matrix, equivalent nodal forces, deflected shape, bending moments and shear forces are provided and verified by an example.
    Additional Material: 3 Ill.
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