ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
α1 glycoprotein
;
Enantioseparation
;
β-blocking agents
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary The enantioselectivity of the α1 glycoprotein chiral stationary phase, Chiral AGP® has been evaluated for a number of β-blocking agents. A correlation has been found between the retention behaviour on this stationary phase and the hydrophobicity of the compounds. The separation factor α is higher for compounds that are well retained. Retention, and thus α, are also controlled by pH and the percentage of organic modifier in the mobile phase.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02262327
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