ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
Retention behaviour of 1,n-halo(alkylthio)alkanes
;
Effect of the halogen atom
;
Effect of the number of methylene groups
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The RPLC retention of 1,n-halo(alkylthio)alkanes on an ODS phase with methanol/water (95%/5%) has been investigated. Replacement of a methyl group in a dialkyl sulphide R-S-R by a halogen atom X, to yield the title compounds X-(CH2)n-S-R, generally results in a retention decrease. This retention loss results either from the halogen atom proper, or from its immediate vicinity, or from a reduced retention contribution of the alkyl units. The methylene groups (n) between halogen and sulphur produce somewhat greater retention than the methylene groups in the alkyl groups R.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02259386
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