ISSN:
0749-1581
Keywords:
Selective relaxation time
;
Double-selective relaxation time
;
Conformation
;
Dynamics
;
Cinnamide derivative
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The dynamics and conformation ofN,N-dimethyl-N-[3-(4-methoxy-trans-cinnamoylamino)propyl]-N-n-dodecylammonium bromide (1) have been established in two solvents (CDCl3 and DMSO-d6) by the use of 13C spin-lattice relaxation rates, non-selective and selective proton spin-lattice relaxation rates and 1H-(1H) NOE experiments. The two solvents affect the conformation of the cinnamide moiety in different ways. This alters the anchor capacity of the moiety towards the alkyl chain and, as a consequence, the dynamics of 1 in CDCl3 and DMSO-d6 show understandable differences. However, the main mean conformations of 1 in both solvents are ‘linear’. The data do not allow the rationalization of the relationship between conformation and sunscreen efficiency.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260301005
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