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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Chromatographia 37 (1993), S. 31-36 
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Diode array detection ; UV library search ; Pharmaceutical compounds
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary A new method for spectral library search based on the dependences of absorbance on the modifier contents in binary mobile phases was developed. The normalisation of spectra by absolute and relative maximum and with respect to the area was tested. The correlation coefficient and the Euclidian distance were used to compare the spectra. The new method of library search allows interpolation of spectra at every composition of eluent in the model range. The range is bracketted by the upper and lower content of modifier in the eluent. In this range five reference spectra were recorded. For validation 34 spectra of pharmaceutical substances in water/methanol and water/acetonitrile mixtures were recorded. In the best case 97 % of spectra were identified correctly. The main problems encountered are that very similar substances e.g. dexa- and betamethasone, have similar spectra as well as similar spectral dependences on the composition of the mobile phase.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 199 (1979), S. 75-81 
    ISSN: 1432-0878
    Keywords: Desert rodents ; Mongolian gerbil (Meriones unguiculati) ; Kidney ; Bowman's capsule ; Pericapsular smooth muscle cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary During the course of a systematic investigation of the renal corpuscles in various desert rodents (Meriones unguiculati, Meriones shawii, Psammomys obesus, and Dipodymis), a thickened Bowman's capsule was observed light microscopically in some kidneys of adult Meriones unguiculati (Mongolian gerbil). Electron microscopic studies show that this unusual finding may depend on the presence of one or two layers of typical smooth muscle cells adjacent to the outer surface of the basal lamina. In the kidneys of other species of desert rats examined, no pericapsular smooth muscle cells were observed.
    Type of Medium: Electronic Resource
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