ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Cyclopeptide  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Analogues of tentoxin: Tools for mechanistic investigations (1997)
    Springer
    International journal of peptide research and therapeutics 4 (1997), S. 283-288 
    Details
    ISSN: 1573-3904
    Keywords: Cyclopeptide ; Tentoxin ; F0F1H+-ATPase ; Herbicide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary Tentoxin [cyclo-(MeAla1-Leu2-MeΔPhe3-Gly4] is a metabolite isolated from a phytopathogenic fungusAlternaria alternata, which induces chlorosis of many plants. This potential natural herbicide binds specifically to the soluble part CF1 of the chloroplastic coupling factor, which is a proton ATP-synthase. The effect of the toxin is concentration dependent: at low concentration it is a powerful inhibitor, while at higher concentration, it stimulates the enzyme. We synthesized tentoxin and we designed new analogues in order to vary the hydrophobicity on the side chain and to study the structure activity relationships. Comparative activities suggest that it is possible to separate inhibitory and activating effects using tentoxin analogues, showing some evidence for the existence of two binding sites with different affinity constant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02442890
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Analogues of tentoxin: Tools for mechanistic investigations (1997)
    Springer
    International journal of peptide research and therapeutics 4 (1997), S. 283-288 
    Details
    ISSN: 1573-3904
    Keywords: Cyclopeptide ; Tentoxin ; F0F1H+-ATPase ; Herbicide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Tentoxin[cyclo-(MeAla1-Leu2-MeΔPhe3-Gly4] is a metabolite isolated from a phytopathogenic fungusAlternaria alternata, which induces chlorosis of many plants. This potentialnatural herbicide binds specifically to the soluble part CF1of the chloroplastic coupling factor, which is a proton ATP-synthase. Theeffect of the toxin is concentration dependent: at low concentration it is apowerful inhibitor, while at higher concentration, it stimulates the enzyme.We synthesized tentoxin and we designed new analogues in order to vary thehydrophobicity on the side chain and to study the structure activityrelationships. Comparative activities suggest that it is possible toseparate inhibitory and activating effects using tentoxin analogues, showingsome evidence for the existence of two binding sites with different affinityconstant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008828301575
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...