ISSN:
1435-1536
Keywords:
Cyanoacrylate nanoparticles
;
propidium iodide
;
nanoparticle
;
fluorescent labelling
;
fluorescent labelling of nanoparticles
;
nanoparticle loading capacity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Abstract Polyalkylcyanoacrylate nanoparticles were labelled with the fluorescent marker propidium iodide to follow their cellular distribution. Fixation of propidium iodide onto the nanoparticles can be achieved by its addition to the polymerization medium after initiating the polymerization process. However, the charged propidium iodide was found to distort the anionic polymerization process. Therefore, polymerization conditions were optimized with regard to the time of marker addition and marker concentration, loading capacity, and monodispersity of the nanoparticles size distribution.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00660304
Permalink
