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  • 1
    ISSN: 1615-6102
    Keywords: Apoptosis ; Atherosclerosis ; Endothelium ; Lipoproteins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Endothelial lesion by oxidized low-density liproproteins (LDL) is one of the first stages in the development of atherosclerosis. The effect of these lipoproteins can range from a functional lesion of the endothelium to death of the endothelial cells by apoptosis. High-density lipoproteins (HDL) are one of the factors which can have a protective effect against the development of atheromatous plaques. The aim of this study is to establish whether the death of endothelial cells by apoptosis induced by oxidized LDLs is prevented by HDLs. ECV304 endothelial cells and bovine aorta endothelial cells were incubated with native LDLs, oxidized LDLs, and a combination of both oxidized LDLs and HDLs. Oxidized LDLs caused a significant increase of mortality mainly by apoptosis. However, when HDLs were added together with oxidized LDLs the percentage of total mortality, the degree of lipoprotein oxidation in the medium, and the percentage of cells in apoptosis were all significantly decreased. HDLs protect against the cytotoxicity of oxidized LDLs possibly by preventing the propagation of the oxidative chain in these lipoproteins.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Liebigs Annalen 2000 (2000), S. 1387-1389 
    ISSN: 1434-193X
    Keywords: Natural products ; Epoxidations ; Asymmetric synthesis ; Fluorine ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: ---The synthesis of enantiomerically and diastereomerically pure (-)-(1R,2R,5R)- and (-)-(1R,2S,5R)-2-fluoro frontalin (7) starting from (+)-(1S)-menthyl-(R)-toluene-4-sulfinate, methylmagnesium bromide, methyl fluoroacetate, 4-pentenyl bromide and diazomethane is described. The absolute stereochemistry was unambiguously determined by X-ray analysis of (+)-(1S,2R,5S,RS)-5, an intermediate in the synthesis of the enantiomeric (+)-(1S,2R,5S)-2-fluoro frontalin (7).
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1434-1948
    Keywords: Silicon ; Silyl anions ; Lithium ; Silanes ; Polysilyl dianions ; α,ω-Dilithiooligosilanes ; Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: (Me3Si)3Si(Me2Si)2(Me3Si)2SiLi (1) and LiSi(Me3Si)2(Me2Si)2Si(Me3Si)2Li (2) were synthesized by the reaction of (Me3Si)3Si(Me2Si)2Si(Me3Si)3 in THF with one or two mol-equivalents, respectively, of MeLi. Both 1 and 2 were characterized spectroscopically and by trapping reactions, and 1 also by X-ray crystallography.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Publication Date: 2015-05-08
    Description: The commonest caligid copepod infesting commercial salmonid netpen systems in southern Chile is described as a new species, Caligus rogercresseyi. This species belongs to the macarovigroup of species within the genus. It differs from Caligus flexispina Lewis 1964, with which it has previously been confused, in several important characters. These include the relatively elongate caudal rami, the proportions of the female genital complex and of the male abdomen, and the armature and ornamentation of the antenna in both sexes. The form of the sensillae associated with the postantennal process and the form of the male maxilliped are identified as possible additional diagnostic characters of the macarovi-group.
    Keywords: Crustacea ; parasitic Copepoda ; salmonid aquaculture ; sea lice ; sp.nov., Chile
    Repository Name: National Museum of Natural History, Netherlands
    Type: Article / Letter to the editor
    Format: application/pdf
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  • 5
    Publication Date: 2024-01-12
    Description: The commonest caligid copepod infesting commercial salmonid netpen systems in southern Chile is described as a new species, Caligus rogercresseyi. This species belongs to the macarovigroup of species within the genus. It differs from Caligus flexispina Lewis 1964, with which it has previously been confused, in several important characters. These include the relatively elongate caudal rami, the proportions of the female genital complex and of the male abdomen, and the armature and ornamentation of the antenna in both sexes. The form of the sensillae associated with the postantennal process and the form of the male maxilliped are identified as possible additional diagnostic characters of the macarovi-group.
    Keywords: Crustacea ; parasitic Copepoda ; salmonid aquaculture ; sea lice ; sp.nov., Chile
    Repository Name: National Museum of Natural History, Netherlands
    Type: info:eu-repo/semantics/article
    Format: application/pdf
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