ISSN:
1434-1948
Keywords:
Clusters
;
Steroids
;
Protonation
;
Carbocations
;
Immunoassay
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The stabilization of carbenium ions by an adjacent organotransition metal moiety has been evaluated using the classical Deno's method as well as a new procedure based on DCI-MS spectrometry. The ability of transition metal clusters to enhance the stability of a proximate carbocationic center in 17α-alkynylestradiol-[OM] derivatives {[OM] = Co2(CO)6; Co2(CO)4(dppm); Mo2Cp2(CO)4; M3(CO)10, M = Ru, Os; HRu3(CO)9} has been related to their capacity to inactivate the estrogen receptor (affinity marker properties).
Additional Material:
7 Ill.
Type of Medium:
Electronic Resource
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