ISSN:
1432-0878
Keywords:
Key words: NADPH diaphorase
;
Nitric oxide
;
Suprachiasmatic nucleus
;
Subparaventricular zone
;
Circadian rhythms
;
Rat (Sprague Dawley).
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract. The ’nicotinamide adenine dinucleotide phosphate diaphorase’ histochemical technique was used as a marker of neuronal nitric oxide synthase to assess the presence of the enzyme in the anterior hypothalamus of the rat. Particular attention was focused on the subparaventricular zone, periventricular area and suprachiasmatic nucleus. The results show that there is strong staining in the anterior hypothalamus particularly in the subparaventricular zone by the perinuclear regions of the suprachiasmatic nucleus, and in the periventricular nucleus. Some diaphorase activity was also seen within the suprachiasmatic nucleus, but this was much weaker than in the surrounding areas. These results, taken together with existing evidence, would further suggest the involvement of nitric oxide in the signal transduction pathway in the suprachiasmatic nucleus.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004410050544
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