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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    The journal of membrane biology 140 (1994), S. 153-161 
    ISSN: 1432-1424
    Keywords: Sinoatrial node cell ; Background current ; Chloride channel ; Angiotensin II ; AT1 receptor ; Protein kinase C
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Single sino-atrial cells from rabbit heart were voltage-clamped using the whole-cell configuration of the patch clamp technique under conditions in which most of the ionic and exchange currents known in pacemaker cardiac cells were minimized. Extracellular angiotensin II (AII) activated a time-independent background current. The current-voltage relation of this current showed an outward rectification. The reversal potential was −20 mV with 156 mm Cl− external solution and 54 mm Cl− internal solution. This reversal potential shifted with changes in the transmembrane Cl− gradient in the fashion expected for a chloride current. Anthracene-9-carboxylic acid and diphenylamine 2-carboxilic acid (chloride channels blockers) were found to be effective in blocking the AII-sensitive current. The linear segment of the current-voltage relation can be totally inhibited by the competitive AII-receptor (AT1) antagonist losartan and by the presence of intracellular protein kinase C inhibitor, whereas the outward rectification is only slightly changed. It is concluded that sino-atrial cells should contain protein-kinase-C-sensitive chloride channels which may be activated by angiotensin II via the stimulation of the AT1 receptors.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Archive of applied mechanics 67 (1996), S. 2-14 
    ISSN: 1432-0681
    Keywords: asymptotic modeling ; Rossby waves ; rotating waves ; rotating stall ; compressors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Summary A comparison between meteorological systems and fluid motions through compressors is proposed. A mathematical analysis analogous to the geophysical one emphasizes characteristic dimensions. A dimensionless kinematic parameter, akin to the Rossby number, emerges, and thus leads to the study of different cases. Two kinds of solutions of rotating waves are presented here. The first describes a Rossby wave propagation in compressors, and the second depicts a limit form of part-span stall.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Archive of applied mechanics 67 (1996), S. 2-14 
    ISSN: 1432-0681
    Keywords: Key words asymptotic modeling ; Rossby waves ; rotating waves ; rotating stall ; compressors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Summary A comparison between meteorological systems and fluid motions through compressors is proposed. A mathematical analysis analogous to the geophysical one emphasizes characteristic dimensions. A dimensionless kinematic parameter, akin to the Rossby number, emerges, and thus leads to the study of different cases. Two kinds of solutions of rotating waves are presented here. The first describes a Rossby wave propagation in compressors, and the second depicts a limit form of part-span stall.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
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