ISSN:
0009-2940
Keywords:
Chiral tin hydrides
;
Chiral hydrogen donors
;
Tin
;
Ligand effects
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The synthesis of the chiral tin bromides 1-4 and hydrides 5-8, containing the potentially bidentate, optically active 2-[ (1 S/R)- 1 -dimethylaminoethyl]phenyl and 2 -[( 1 S) - 1 -dimethylamino-2,2-dimethylpropyl]phenyl ligands, is reported. The tin hydrides 5-8, with the tin atom as the stereogenic centre, were isolated as diastereomeric mixtures with diastereomeric ratios of dr = 50:50 up to dr = 80:20. The absolute configuration of ( - ) - (1 S)- 1 - (2-bromophenyl) -2,2-dimethylpropylamine [(S)-10] was determined by single-crystal X-ray structure analysis.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19971301030
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