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  • 1
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 29 (1983), S. 717-725 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A model, which utilizes a Monte Carlo simulation, of the sintering and the redispersion of supported metal catalysts is presented and compared with experimental data from a Pt/Al2O3 system. The model is based on an atomic migration mechanism, but includes instantaneous diffusion and coalescence of crystallites of size 〈1 nm in reducing and inert atmospheres. It was found that behavior in reducing, oxidizing and inert atmospheres could be predicted.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 8 (1974), S. 321-338 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The use of conventional rigid metal plates (modulus of elasticity 30 × 106 psi) for internal fixation of difficult long bone fractures may paradoxically weaken the fractured bone through a process of osteoporosis secondary to protection of the bone from stress. The hypothesis being studied which has stimulated the present work is that a new composite plate made of less rigid material but with similar geometry to stainless steel plates may promote fracture union without the complication of osteopenia. This new composite material has a modulus of elasticity similar to that of bone (approximately 3 × 106 psi) which is more than an order of magnitude lower than that of stainless steel, yet the fracture strength of this new composite material (35,000 psi) is approximately one-half that of stainless steel.The ability to fix diaphyseal fractures by composite plates was studied by implanting these plates in the left (experimental) radii of six dogs with transverse mid-shaft osteotomies. The right (control) radii had similar transverse osteotomies, but were plated by conventional metal plates equal in size to the new composite plates. Four months postsurgery, all experimental and control fractures had healed.Biomechanical tests of the excised radii using a torsional loading apparatus showed there were no significant differences in strength, fracture energy, angular deformation, or maximum shearing stress when comparing the experimental to the control radii. The results are sufficiently promising to warrant additional long-term experiments investigating this concept of internal fixation.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 8 (1974), S. 85-97 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: A study of the tissue compatibility of aluminum oxide implants under different stress conditions in rabbits was performed over four- and eight-week implantation periods. The specific objectives were to examine endosteal bone ingrowth into aluminum oxide coneshaped plugs in amputated tibiae, while additional pellet-shaped implants in the tibiae and femora of rabbits with amputated and nonamputated limbs were studied to determine: (1) if the degree of loading placed on the amputated limb was sufficient to promote bone activity, (2) the degree of inertness and/or toxicity of the aluminum oxide implants, and (3) a possible cause of bone spurs.The results of the radiographic, histologic and microradiographic analyses of the in vivo implants demonstrated that there was little mineralized bone ingrowth into the coneshaped aluminum oxide implants in the amputated tibiae. The study also showed that the aluminum oxide pellet implants in the tibiae and femora of the nonamputated limbs demonstrated excellent mineralized bone ingrowth into surface and internal pores. By comparing these results with the incomplete ingrowth into corresponding pellet implants in the tibiae and femora of amputated limbs, it was determined that a lack of weight bearing and damage to the musculature and vascularity following amputation were interfering with the normal bone activity and therefore bone ingrowth.Angiographs and radiographs of the amputated tibiae demonstrated that bone spurs were present and that they originated at the site of the periosteal damage. Their cause was believed to be associated with an increase in the vascularity of the adjacent tissues.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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