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  • Chemical Engineering  (1)
  • healthy volunteers  (1)
  • 1975-1979  (2)
  • 1910-1914
  • 1900-1904
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Keywords
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Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of hexobarbital in man after intravenous infusion (1975)
    Springer
    Journal of pharmacokinetics and pharmacodynamics 3 (1975), S. 1-11 
    Details
    ISSN: 1573-8744
    Keywords: hexobarbital pharmacokinetics ; intravenous infusion ; healthy volunteers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The plasma levels of hexobarbital in humans were determined during and after a 30-min or 60-min zero-order intravenous infusion. Hexobarbital kinetics could be described by conceiving the body to exhibit two compartments. The plasma concentrations were fitted to the postinfusion equation and the parameters intrinsic to the two- compartment open model were estimated. The elimination half-life varied considerably among the 14 individuals (160–441 min), which could mainly be explained by the greatly varying metabolic clearance of the compound (123–360 ml /min). The apparent volume of distribution per kilogram of body weight was relatively constant (1.10±0.12 liters/kg).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01066591
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  • 2
    Electronic Resource
    Electronic Resource
    Kinetics of fast (RIM) urethane polymerizationPresented in part at the AIChE Annual Meeting, Chicago (Dec. 1976). (1978)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 18 (1978), S. 1012-1018 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The kinetics of the dibutyltin dilaurate catalyzed bulk polymerization of 4,4′-diphenylmethane diisocyanate (MDI) with poly-∊-caprolactone were studied by infared spectroscopy and adiabatic temperature rise. The overall reaction order was found to change from 3/2 to 2 with increasing temperature. At temperatures above 80°C, the order with respect to catalyst was found to decrease with concentration from 1 to 1/2. The results were consistent with a Michaelis Menten type kinetic scheme.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760181308
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    Paper (German National Licenses)
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