ISSN:
1040-0397
Keywords:
Ion-selective electrodes
;
Membrane sensors
;
In vivo sensors
;
pH
;
Potassium ion
;
Calcium ion sensors
;
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Potentiometric ion-sensitive planar microelectrode arrays, and amperornetric enzyme-containing biosensors were fabricated by photolithographic microelectronic technology on a flexible polyimide substrate. The steps of the microelectronics processing are summarized in more detail than previously described. The ion-selective electrodes were tested in blood serum, whole blood, and in the hamstring muscle of anesthetized rabbits. The test and performance characteristics of planar pH are emphasized, and K+, Na+, and Ca2+ data are included in this review. New applied results are presented from experiments where the electrodes have been implanted into an in situ porcine beating heart at the midmyocardial depth in order to monitor H+ and K+ changes during the course of coronary artery occlusion.
Additional Material:
6 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/elan.1140070910
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