ISSN:
1573-3904
Keywords:
CD
;
Endopeptidase
;
Micro-environment
;
NMR
;
Subtilisin BPN′
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract H-NMR studies of the bovine insulin S-sulfonatedB-chain are reported in H2O/D2O (9/1) and inglycerol-d5 (5 M) using two-dimensional NMRspectroscopy. The first results show that the oxidizedinsulin B-chain secondary structure differs from thatof native insulin by a loss of the α-helixbetween the two disulfide bridges and that theglycerol favours the structuring of the peptide.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1008822230053
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