Publication Date:
1982-03-05
Description:
Oropouche virus (arbovirus family Bunyaviridae, Simbu serological group) was experimentally transmitted from man to hamster by the bite of the midge Culicoides paraensis. Infection rates and transmission rates were determined after the midge had engorged on patients with viremia. The threshold titer necessary to enable infection or transmission by the midges was approximately 5.3 log10 of the median lethal dose of the virus in suckling mice per milliliter of blood. Transmission was achieved 6 to 12 days after C. paraensis had taken the infective blood meal. This represents conclusive evidence of transmission of an arbovirus of public health importance to man by a member of the Ceratopogonidae family.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pinheiro, F P -- Travassos da Rosa, A P -- Gomes, M L -- LeDuc, J W -- Hoch, A L -- New York, N.Y. -- Science. 1982 Mar 5;215(4537):1251-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6800036" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Bunyaviridae/*physiology
;
Bunyaviridae Infections/*transmission
;
Ceratopogonidae/*microbiology
;
Cricetinae
;
Disease Models, Animal
;
Humans
;
Insect Vectors/*microbiology
;
Simbu virus/*physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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