ISSN:
0570-0833
Keywords:
Biosynthesis
;
Amino acids
;
Shikimic acid
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Microorganisms synthesize the aromatic amino acids phenylalanine, tyrosine, and tryptophan, as well as the related compounds p-aminobenzoic acid, tetrahydrofolic acid, p-hydroxybenzoic acid, ubiquinone, vitamin K, and nicotinic acid, by a highly branched route passing through shikimic acid. The biosynthesis is not regulated in the same way in all the organisms studied. The regulation is strongly dependent on the ability of the enzymes involved to be resolved into isozymes, their ability to be inhibited, and their activation, repression, and induction.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/anie.196803501
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