Publication Date:
1995-09-29
Description:
A nuclear magnetic resonance imaging (MRI) method is presented for quantitatively mapping the physical response of a material to harmonic mechanical excitation. The resulting images allow calculation of regional mechanical properties. Measurements of shear modulus obtained with the MRI technique in gel materials correlate with independent measurements of static shear modulus. The results indicate that displacement patterns corresponding to cyclic displacements smaller than 200 nanometers can be measured. The findings suggest the feasibility of a medical imaging technique for delineating elasticity and other mechanical properties of tissue.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Muthupillai, R -- Lomas, D J -- Rossman, P J -- Greenleaf, J F -- Manduca, A -- Ehman, R L -- CA51124/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1995 Sep 29;269(5232):1854-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Mayo Clinic and Foundation, Rochester, MN 55905, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7569924" target="_blank"〉PubMed〈/a〉
Keywords:
Acoustic Stimulation
;
Animals
;
Biomechanical Phenomena
;
Elasticity
;
Gels
;
Kidney/*anatomy & histology/physiology
;
Kidney Cortex/anatomy & histology/physiology
;
Kidney Medulla/anatomy & histology/physiology
;
Magnetic Resonance Imaging/*methods
;
Magnetic Resonance Spectroscopy
;
Mathematics
;
Mice
;
Sepharose
;
Stress, Mechanical
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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