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  • Biochemistry and Biotechnology  (3)
  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 47 (1995), S. 703-712 
    ISSN: 0006-3592
    Keywords: biofilm modeling ; detachment ; porous media ; biobarriers ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A packed bed biofilm reactor inoculated with pure culture Pseudomonas aeruginosa was run under high substrate loading and constant flow rate conditions. The 3.1-cm-diameter cylindrical reactor was 5 cm in length and packed with 1-mm glass beads. Daily observations of biofilm thickness, influent and effluent glucose substrate concentration, and effluent dissolved and total organic carbon were made during the 13-day experiment. Biofilm thickness appeared to rech quasi-steady-state condition after 10 days. A published biofilm process simulation program (AQUASIM) was used to analyze experimental data. Comparison of observed and simulated variables revealed three distinct phases of biofilm accumulation during the experiment: an initial phase, a growth phase, and a mature biofilm phase. Different combinations of biofilm and mass transport process variables were found to be important during each phase. Biofilm detachment was highly correlated with shear at the biofilm surface during all three phases of biofilm development. © 1995 John Wiley & Sons, Inc.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 49 (1996), S. 172-184 
    ISSN: 0006-3592
    Keywords: biofilm ; diffusion ; model ; mixed-culture ; simulation ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: About 10 years ago a set of mass balance equations for mathematical modeling of mixed-culture biofilms (MCBs) was presented. That model was able to describe the progression of the biofilm thickness and the spatial distribution and development in time of particulate and dissolved components in the biofilm as a function of transport and transformation processes. Experimental observations made in the past years have shown that some of the assumptions made in that MCB model were too simple. Therefore, an extended MCB model with additional processes has been developed. This model includes a more flexible description of transport of dissolved components in the biofilm and considers diffusive transport of particulate components in the biofilm solid matrix, changes of the biofilm liquid phase volume fraction (porosity), and simultaneous detachment and attachment of cells and particles at the biofilm surface. The extended MCB model is implemented in AQUASIM, a new computer program designed for the analysis of aquatic systems, which is used here to illustrate and discuss the effect of the additional processes on MCB behavior. © 1996 John Wiley & Sons, Inc.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 28 (1986), S. 314-328 
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Using a continuum approach and observing conservation principles, an analytical mathematical model of microbial interaction in biofilms was developed. The model predicts changes in biofilm thickness and describes the dynamics and spatial distribution of microbial species and substrates in the film. It allows for biomass detachment due to shear stress and sloughing, external mass transfer limitations, as well as variations in substrate concentrations in the bulk liquid. A computer implementation of the model is provided using an example of heterotrophicautotrophic competition to illustrate how the observed phenomena can be numerically reproduced and indicating how they might affect overall biofilm performance.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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