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  • 1
    Electronic Resource
    Electronic Resource
    Effect of polyenyl phosphatidyl choline on clofibrate-induced increase in LDL cholesterol (1979)
    Springer
    European journal of clinical pharmacology 15 (1979), S. 15-19 
    Details
    ISSN: 1432-1041
    Keywords: clofibrate ; polyenyl phosphatidyl choline ; hyperlipoproteinemia ; LDL cholesterol ; coronary heart disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary In a double-blind, randomised, cross-over trial clofibrate and a combination of polyenyl phosphatidyl choline (PPC) plus clofibrate were tested in 67 patients with hyperlipoproteinemia. Each treatment lasted for 4 weeks and was separated by a 4 week placebo period. The daily doses were clofibrate 1.2 g and PPC 1.8 g + clofibrate 1.2 g, respectively. The results revealed that polypenyl phosphatidyl choline prevented the elevation of LDL-cholesterol induced by clofibrate treatment, and that the lipid-lowering potency of the combination did not differ significantly from that of clofibrate. Since elevation of LDL-cholesterol is considered to increase the risk of coronary heart disease, the combination appears to offer a therapeutic advantage. Despite the significance of this clinical observation, a final decision may only be obtained from a prospective, long term investigation in patients with coronary heart disease and hyperlipoproteinemia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00563553
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  • 2
    Electronic Resource
    Electronic Resource
    Plant uptake of bicarbonate as measured with the11C isotope (1979)
    Springer
    Plant and soil 51 (1979), S. 431-435 
    Details
    ISSN: 1573-5036
    Keywords: Bicarbonate ; Bush beans ; 11C ; Cation-anion ; CO2 fixation ; Galenia ; Tracer ; Uptake
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary 11C which is cyclotron produced by14N(P, α)11C(half-life 20.1M) was use as a tracer of bicarbonate to determine its movements from a nutrient solution through roots to stems and leaves of bush bean plants (Phaseolus vulgaris L. var. Improved Tendergreen). The short time involved and the high solution pH minimized the need for use of the Hederson Hasselbach equation for activity correction. Quantities of11C did move into roots, stems and leaves with a sharp decreasing gradient (root/stem=14.5, stems/leaves=11.7) More11C moved into plants with KHCO3 than with NaHCO3. The (NH4)2SO4 enhanced11C uptake and KNO3 than with competition indicated possibility of some uptake of HCO 3 − . In an experiment withGalenia pubescens (Eckl. and Zeyh.) Druce, the11C was more readily moved to stems and leaves than in bush bean indicating substantial uptake of HCO 3 − .
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02197790
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    Paper (German National Licenses)
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