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Cyclotron production of I-123: An evaluation of the nuclear reactions which produce this isotope (1970)

Wellman, H. N. ; Scholz, K. L. ; Sodd, V. J. ; [et al.]

In: CASI

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Publication Date: 2019-06-27

Description: The use of the various nuclear reactions is described by which I-123,a low radiation dose radiopharmaceutical, can be cyclotron-produced. Methods of directly producing I-123 and those which indirectly produce the radionuclide through the beta (+) decay of its nautral precursor, Xe-123. It is impossible to separate from the radioiodine contaminants, notably I-124, which occur in the direct method. Thus, it is preferable to produce pure I-123 from Xe-123 which is easily separated from the radioiodines. Among the characteristics of I-123 is the capability of reducing the patient dose in a thyroid uptake measurement to a very small percentage of that delivered by the more commonly used I-131.

Keywords: BIOSCIENCES

Type: NASA-TM-X-67594 , BRH/DMRE-70-4

Format: application/pdf

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