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  • 1
    Publication Date: 2011-08-16
    Description: This study documents bedrest-induced metabolic and physiologic changes in six untrained men exposed, following a two-week period of simulated weightlessness, to possible +Gz acceleration profiles anticipated for Space Shuttle vehicle travel. All subjects demonstrated decreased +Gz tolerance following simulated weightlessness. While only one of six subjects could not tolerate the +Gz profile in the control phase of the study, three of the six could not complete the postbed-rest study. The use of an inflated standard Air Force cutaway G-suit improved +Gz tolerance in all subjects, but two of six subjects still failed to complete the profile. These findings are discussed in reference to the selection of untrained humans for Space Shuttle vehicle travel.
    Keywords: BIOSCIENCES
    Type: Journal of Applied Physiology; 36; June 197
    Format: text
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  • 2
    Publication Date: 2019-06-27
    Description: The magnitude of physiologic changes which are known to occur in human subjects exposed to varying levels of + G sub Z acceleration following bed rest simulation of weightlessness was studied. Bed rest effects were documented by fluid and electrolyte balance studies, maximal exercise capability, 70 deg passive tilt and lower body negative pressure tests and the ability to endure randomly prescribed acceleration profiles of +2G sub Z, +3G sub Z, and +4G sub Z. Six healthy male volunteers were studied during two weeks of bed rest after adequate control observations, followed by two weeks of recovery, followed by a second two-week period of bed rest at which time an Air Force cutaway anti-G suit was used to determine its effectiveness as a countermeasure for observed cardiovascular changes during acceleration. Results showed uniform and significant changes in all measured parameters as a consequence of bed rest including a reduced ability to tolerate +G sub Z acceleration. The use of anti-G suits significantly improved subject tolerance to all G exposures and returned measured parameters such as heart rate and blood pressure towards or to pre-bed-rest (control) values in four of the six cases.
    Keywords: BIOSCIENCES
    Type: NASA-TM-X-62311
    Format: application/pdf
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