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  • 1
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    Evaluation of the hazard from exposure to electron irradiation simulating that in the synchronous orbit (1972)
    In:  CASI
    Details
    Publication Date: 2016-06-07
    Description: The electron spectrum predicted for the synchronous orbit was simulated to determine the effects that might occur to astroscientists exposed to such irradiation while on a prolonged space station mission in that region. Miniature pigs were exposed to monoenergetic and spectral-fractionated irradiations with 0.5 to 2.1 MeV electrons. Clinical and pathological alterations observed in biopsies were correlated with depth-dose pattern and length of post irradiation period up to one year. With monoenergetic electrons, the lowest dose causing a recognizable lesion was 1450 rad and with increasing dose lesions appeared earlier and were more severe. At the highest dose given, 2650 rad, ulceration extending into the dermis was present by twenty one days and required about four months for complete healing. Spectral-fractionated irradiations, in which the total dose range was essentially comparable to that of the monoenergetic series, resulted in very minimal outer dermis edema at 1790 rad and at no dose employed did necrosis of epidermis or ulceration into dermis occur.
    Keywords: BIOSCIENCES
    Type: Proc. of the Natl. Symp. on Nat. and Manmade Radiation in Space; p 665-671
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 2
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    RBE for late somatic effects in mice irradiated with 60 MeV protons relative to X-rays. (1971)
    In:  Other Sources
    Details
    Publication Date: 2019-07-13
    Description: Investigation of the relative biological effectiveness of energetic protons for the induction of somatic effects in a mammal (mice) following whole body irradiation. The proton energy used approximates the mean energy for proton spectra accompanying solar events. The effects on longevity and the incidence of major neoplastic diseases are summarized. The results obtained suggest that medium energy proton irradiation is no more effective, and on the whole, probably less effective, than conventional X radiation for the induction of late radiation effects in the mouse.
    Keywords: BIOSCIENCES
    Type: CERN-71-16 , International Congress on Protection Against Accelerator and Space Radiation; Apr 26, 1971 - Apr 30, 1971; Geneva; Switzerland
    Format: text
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    NASA TECHNICAL REPORTS
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