ISSN:
1040-7685
Keywords:
gas chromatography (GC)
;
multidimensional chromatography (MDC)
;
parallel column gas chromatography (PCGC)
;
thermodynamic retention parameters
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A parallel column gas chromatography (PCGC) methodology that simultaneously collects retention information on multiple stationary phases is presented. The multidimensional PCGC configuration links a precolumn in series with a set of parallel analytical columns (having different stationary phases) all connected to a single detector. GC peaks heartcut from the precolumn are detected as a series of peaks due to retention differences on parallel columns. This provides a GC retention pattern that is characteristic of the analyte, the stationary phase array, and the conditions of the analysis. PCGC peak patterns observed for groups of C8, C9, and C10 compounds are presented. The use of PCGC with infrared and mass spectral detectors is reported. A methodology to account for changes in GC operating parameters using relative retentions of analytes to internal standards is presented. The first use of thermodynamic retention parameters to model retention behavior on parallel analytical columns under different temperature profiles is presented. Retention predictions within 0.3-0.6% of experimental values are reported. These results indicate that PCGC has potential as a general qualitative analysis tool. Future efforts to calibrate retention predictions, to transport PCGC results between instruments, and to optimize the number of parallel columns are proposed. © 1995 John Wiley & Sons, Inc.This article is a US Government work and, as such, is in the public domain in the United States of America.
Additional Material:
13 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mcs.1220070602
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