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  • 1
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    The stomach signals satiety (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-07-14
    Description: Inflatable pyloric cuffs and stomach tubes were implanted in rats. With the cuff inflated and a valve to limit intragastric pressure to that accompanying normal satiety, they drank only as much when they had been deprived of food for 12 hours as without inflation of the cuff. However, they overdrank with the cuff inflated when they had been water deprived for 12 hours. When 10 ml of milk was withdrawn from the stomach with the cuff inflated, compensatory drinking occurred. Further, compensatory drinking also occurred when milk escaped from the stomach into the duodenum. Satiety signals thus arise from the stomach.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Deutsch, J A -- Young, W G -- Kalogeris, T J -- New York, N.Y. -- Science. 1978 Jul 14;201(4351):165-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/663647" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Drinking Behavior/physiology ; Duodenum/physiology ; Food Deprivation ; Male ; Rats ; Satiation/*physiology ; Satiety Response/*physiology ; Stomach/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Prenatal exposure to prednisone in humans and animals retards intrauterine growth (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-27
    Description: Prednisone treatment for infertility and subsequent pregnancy maintenance in humans resulted in a significant decrease in the birth weight of full-term infants and a marked increase in the percentage of newborn infants weighing 2500 grams or less, that is, "light for dates" in comparison to control offspring. A parallel experiment with mice indicated that the reduction of birth weight was caused by exposure to corticosteroids rather than to maternal disease or malfunction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Reinisch, J M -- Simon, N G -- Karow, W G -- Gandelman, R -- New York, N.Y. -- Science. 1978 Oct 27;202(4366):436-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/705336" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Birth Weight/*drug effects ; Female ; Fetus/*drug effects ; Humans ; *Infant, Low Birth Weight ; Infant, Newborn ; Male ; Mice ; Prednisone/*adverse effects ; Pregnancy/*drug effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Chicken gizzard: relation between calcium-activated phosphorylation and contraction (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-05-04
    Description: Of the proteins in mechanically disrupted chicken gizzard fibers (no functional sarcolemma) only the 20,000-dalton light chains of myosin underwent large Ca2+-and Sr2+-dependent changes in phosphorylation. Phosphorylation closely corresponded with the Ca2+- and Sr2+-activated tensions. Adenosine 5'-O (3'-thiotriphosphate) only in the presence of Ca2+ induced irreversible Ca2+-insensitive activation of tension and thiophosphorylation of the 20,000-dalton light chains, and blocked incorporation of 32P from [gamma-32P]adenosine triphosphate into the myosin light chains.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hoar, P E -- Kerrick, W G -- Cassidy, P S -- New York, N.Y. -- Science. 1979 May 4;204(4392):503-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/432654" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Calcium/*pharmacology ; Chickens ; Gizzard/*physiology ; In Vitro Techniques ; Molecular Weight ; Muscle Contraction/*drug effects ; Muscle, Smooth/*physiology ; Myosins/*metabolism ; Phosphorylation ; Protein Kinases/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Mercury concentrations in Pacific hake, Merluccius productus (Ayres), as a function of length and latitude (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-06-30
    Description: Mercury concentrations in Pacific hake increase with fish size and with the latitude of collection. While the mercury-size trend is consistent with data for other species, the latitudinal trend is opposite to that reported for other fishes over the same geographical area. Consequently, latitudinal trends of mercury concentrations in fishes do not necessarily indicate trends of mercury concentrations in water. Food habits and metabolism may cause the observed variations.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cutshall, N H -- Naidu, J R -- Pearcy, W G -- New York, N.Y. -- Science. 1978 Jun 30;200(4349):1489-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/663631" target="_blank"〉PubMed〈/a〉
    Keywords: Age Factors ; Animals ; Environment ; Fishes/*metabolism ; Mercury/*metabolism ; Water Pollutants/*metabolism ; Water Pollutants, Chemical/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    Cardiopulmonary changes in kittens during sleep (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-09-07
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Guntheroth, W G -- New York, N.Y. -- Science. 1979 Sep 7;205(4410):1040-1.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472729" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chick Embryo ; Hemodynamics ; Respiration ; Sleep/*physiology ; Sudden Infant Death/physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Membrane surface potential changes may alter drug interactions: an example, acetylcholine and curare (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-03-30
    Description: Curare is known to be less effective as an acetycholine antagonist when the divalent cation concentration of the extracellular solution is increased. This observation can be accounted for by the negative surface potential on the end plate; an increase in divalent cation concentration decreases the negativity of the surface potential and thereby lowers the concentrations of cations at the membrane-solution interface. The concentration of divalent cations, such as curare, will be reduced more than the concentration of univalent cations, such as acetylcholine. The observations can be accounted for by a surface potential of about -50 millivolts. The same principle can explain the reported actions of divalent cations on the affinity of receptors for acetylcholine. The effects of surface potential on concentrations at active sites may play an important role in drug interactions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Van der Kloot, W G -- Cohen, I -- New York, N.Y. -- Science. 1979 Mar 30;203(4387):1351-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/424757" target="_blank"〉PubMed〈/a〉
    Keywords: Acetylcholine/*pharmacology ; Animals ; Anura ; Curare/*pharmacology ; Drug Interactions ; Electric Conductivity ; Ions ; *Membrane Potentials ; Models, Biological ; Motor Endplate/*physiology ; Neuromuscular Junction/*physiology ; Receptors, Cholinergic/*drug effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    Feeding and behavioral activation in infant rats (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-13
    Description: Three-day-old rats that were separated from their mothers and deprived of food were found to be capable of feeding either from small puddles of milk or when milk was infused into the front of their mouths. Such feeding was accompanied by a dramatic increase in behavioral activity and only occurred in a warm environment. These data demonstrate that neural systems for ingestive behavior are present at birth and suggest the existence of feeding-related arousal or motivational systems.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hall, W G -- New York, N.Y. -- Science. 1979 Jul 13;205(4402):206-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451591" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Animals, Newborn/*physiology ; Behavior, Animal/*physiology ; Feeding Behavior/*physiology ; Food Deprivation ; Movement ; Rats ; Temperature ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    Appetitive learning in 1-day-old rat pups (1979)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1979-07-27
    Description: One-day-old rat pups learned to probe upward into a terry-cloth-covered paddle when they were rewarded with small infusions of milk into their mouths. In the presence of two paddles, discriminable on the basis of odor and position in the test container, the pups learned to probe into the paddle that provided them with milk. These experiments demonstrate (i) that milk may serve as a reinforcer to deprived rat pups and (ii) that pups as young as 1 day are capable of appetitive learning.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Johanson, I B -- Hall, W G -- New York, N.Y. -- Science. 1979 Jul 27;205(4404):419-21.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451612" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Animals, Newborn ; *Feeding Behavior ; Food Deprivation ; *Learning ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Intraspecific evidence for the function of single and double cones in the teleost retina (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-20
    Description: Retinal growth in young Sebastes diploproa involves the succession of three distinct cone patterns. Development of the final pattern with the loss of single cones occurs in close temporal association with a permanent migration from the surface to deep water. The results suggest that loss of single cones depends upon the change in environment and that the loss occurs through fusion to double elements.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Boehlert, G W -- New York, N.Y. -- Science. 1978 Oct 20;202(4365):309-11.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/694534" target="_blank"〉PubMed〈/a〉
    Keywords: Age Factors ; Animals ; Environment ; Fishes/*physiology ; Light ; Photoreceptor Cells/*physiology ; Retina/ultrastructure ; Species Specificity ; Trout/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 10
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    Chronic focal epileptiform discharges induced by injection of iron into rat and cat cortex (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-06-30
    Description: A single injection of 5 or 10 microliters of ferrous or ferric chloride into rat or cat sensorimotor cortex resulted in chronic recurrent focal paroxysmal electroencephalographic discharges as well as behavioral convulsions and electrical seizures. Recurrent focal epileptiform discharge caused by cortical injection of iron salts suggests that the development of human posttraumatic epilepsy may depend, in part, on the neurochemical alterations induced by the principal metallic ions found in whole blood.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Willmore, L J -- Sypert, G W -- Munson, J V -- Hurd, R W -- New York, N.Y. -- Science. 1978 Jun 30;200(4349):1501-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/96527" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cats ; Cerebral Cortex/*drug effects/physiopathology ; *Disease Models, Animal ; Electrophysiology ; Epilepsies, Partial/*chemically induced ; Ferric Compounds ; Ferrous Compounds ; *Iron ; Rats ; Seizures/*chemically induced/physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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