Publication Date:
1983-06-17
Description:
Weak, pulsing electromagnetic fields can modify biological processes. The hypothesis that responses to such induced currents depend on pulse characteristics was evaluated by using transcription as the target process. Two pulses in clinical use, the repetitive single pulse and the repetitive pulse train, were tested. These pulses produced different results from each other and from controls when transcription in dipteran salivary gland cells was monitored with tritiated uridine in transcription autoradiography, cytological nick translation, and analysis of isolated RNA fractions. The single pulse increased the specific activity of messenger RNA after 15 and 45 minutes of exposure. The pulse train increased specific activity only after 45 minutes of exposure.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Goodman, R -- Bassett, C A -- Henderson, A S -- 1ROI CA 29340/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1983 Jun 17;220(4603):1283-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6857248" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Autoradiography
;
Diptera
;
Dose-Response Relationship, Radiation
;
*Electromagnetic Fields
;
*Electromagnetic Phenomena
;
RNA, Messenger/metabolism
;
Salivary Glands/metabolism
;
Transcription, Genetic/*radiation effects
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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