ISSN:
0947-3440
Schlagwort(e):
Angucyclines
;
Diels-Alder reactions
;
Photooxygenation
;
Methoxylation
;
Osmylation
;
X-ray
;
Chemistry
;
Organic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
Osmylation of the Diels-Alder adduct 3 afforded the cis-diol 4, which was dehydrated by acid treatment to the phenol 6. Reaction with tetrafluoroboric acid converted the diol 4 by intramolecular acyl shift into the acetate 7. The relative stereochemistry of 7 was determined by single-crystal X-ray analysis. Photooxygenation of 4 afforded the C-1 carbonyl compound 8 and treatment with sulfuric acid the silanol 9. Functionalization of C-6 was achieved by treatment of 4 with methanolic KOH to yield the cis-methyl ether 11.
Zusätzliches Material:
1 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/jlac.1995199511277
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