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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Lasers in medical science 6 (1991), S. 271-279 
    ISSN: 1435-604X
    Keywords: Angioplasty ; Arterial wall injury ; Smooth muscle cell ; Arterial wall healing ; Restenosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract Substantial damage is inflicted on the arterial wall by conventional balloon angioplasty as well as by newer interventional devices. Restenosis seems to be due to an exaggerated, albeit normal healing response of the arterial wall to interventional injury. Since the relationship between arterial wall damage and restenosis is not entirely clear, experimental studies were performed in the normal rabbit to assess the effects of the nature and the extent of injury on the subsequent myointimal proliferation. The results suggest that the myointimal proliferation is an aspecific repair response to wall injury. The results further suggest an on-off character of myointimal proliferation after injury, which would imply that alternative, less damaging interventional methods may not reduce the problem of restenosis.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Lasers in medical science 6 (1991), S. 223-233 
    ISSN: 1435-604X
    Keywords: Angioplasty ; Recanalization ; Laser ; Balloon ; Intravascular ultrasound ; Restenosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract The current state of clinical laser angioplasty is reviewed. Compared to balloon dilation at the beginning of the past decade, both peripheral and coronary laser angioplasty devices produce better results. Compared to current balloon angioplasty techniques, however, laser angioplasty does not seem to offer improved initial or long term results. Intravascular ultrasound imaging may help to improve laser ablation of atherosclerotic plaque. It remains to be established, however, whether precise debulking of the obstruction will result in a reduced restenosis rate compared to balloon angioplasty.
    Type of Medium: Electronic Resource
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