ISSN:
0030-4921
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The barriers to rotation of the 3-substituent in six 3-RCH2-4-Me-δ4-thiazoline-2-thiones (R = Me, Et, Pr, Isobu, Isopr,t-Bu) and in two analogous methiodides have been measured by the 1H DNMR technique. The barriers are discussed in relation to the possible conformations of the transition states, and comparisons are made with barriers to rotation of the same substituents in other frameworks. It is concluded that the relative steric effects are strongly dependent on the framework and that, in general, a conformational analysis of the individual cases is necessary to understand the steric effects of alkyl groups.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1270140208
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